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Iranian Journal of Medical Sciences، جلد ۴۲، شماره ۵، صفحات ۴۹۷-۰

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عنوان انگلیسی A Rare Case of Fixed Drug Eruption due to Ondansetron
چکیده انگلیسی مقاله Abstract Fixed drug eruption (FDE) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug. FDE is characterized by the appearance of a single or multiple sharply demarcated violaceous erythematous plaques which heal with residual hyperpigmentation. A 27-year-old woman presented with multiple dark patches over her eyelids, mouth, lips, and shoulders of 1 week’s duration. These lesions followed multiple erythematous plaques over the same areas which appeared within 4 hours of the intake of an ondansetron tablet, 12 days previously. The case was diagnosed as post-inflammatory hyperpigmentation following ondansetron-induced FDE. There was an identical episode 1 year earlier due to the intake of the same drug. The causality assessment pointed toward a probable/likely association as per the Naranjo algorithm and the WHO–UMC scale. There have been only a few cases of FDE due to ondansetron in the reported literature.
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نویسندگان مقاله aditi maitra | aditi maitra
department of ophthalmology, calcutta national medical college, kolkata, india


shashwat bhattacharyya | shashwat bhattacharyya
department of clinical and experimental pharmacology, calcutta school of tropical medicine, kolkata, india;


sabyasachi paik | sabyasachi paik
department of dermatology and venereology, calcutta school of tropical medicine, kolkata, india


prerna pathak | prerna pathak
department of clinical and experimental pharmacology, calcutta school of tropical medicine, kolkata, india;


santanu کومار tripathi | santanu kumar tripathi



نشانی اینترنتی http://ijms.sums.ac.ir/index.php/IJMS/article/view/2851
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/147/article-147-433350.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Case Report(s)
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