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Iranian Journal of Public Health، جلد ۴۳، شماره ۴، صفحات ۴۴۱-۵۲
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عنوان انگلیسی Prevalence and Genetic Analysis of Bitter Taste Perception for Phenylthiocarbamide (PTC) Among Some Muslim Populations of Uttar Pradesh, India.
چکیده انگلیسی مقاله The ability to taste Phenylthiocarbamide (PTC), a bitter organic compound, described as a bimodal autosomal trait is widely used to know the heritable trait in both genetic and anthropological studies. The present study was carried out to analyze the prevalence of PTC taste sensitivity and to determine the gene frequencies among some Muslim populations of Uttar Pradesh, India. This study has some physiological relevance to highlight the adaptability of endogamous groups to behavioral traits in the same place.Unrelated, healthy individuals of both sexes (Male-403, Female-418) belonging to different populations of Uttar Pradesh, India were randomly selected with the age range of 16-45 years observed for phenylthiocarbamide to taste sensitivity. PTC tasting ability was measured by using a serial dilution method of Harris and Kalmus.The phenotypic frequency of tasters was higher as compared to non-tasters, and the same is statistically significant (χ(2)= 11.92, df = 5, P = 0.036). There were more females among tasters (67.94%) than males (64.76%). This observation was statistically significant (χ(2) = 14.79, df = 5, P = 0.011).The frequency of PTC tasters is greater than non-tasters and the females have lower non-taster pheno-types as compared to males. This type of study will provide background information about genetic structure of population and serves as useful interaction of genetics, food preferences and dietary patterns.
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نویسندگان مقاله ruqaiya حسین | ruqaiya hussain
human genetics and toxicology tab, section of genetics, department of zoology, aligarh muslim university , aligarh, uttar pradesh, india.


ahsana شاه | ahsana shah
human genetics and toxicology tab, section of genetics, department of zoology, aligarh muslim university , aligarh, uttar pradesh, india.


محمد افضل | mohammad afzal
human genetics and toxicology tab, section of genetics, department of zoology, aligarh muslim university , aligarh, uttar pradesh, india.
نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/4108
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