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Iranian Journal of Public Health، جلد ۳۷، شماره ۴، صفحات ۱۰۳-۱۰۸
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عنوان انگلیسی Association between Iron Status and Lipid Peroxidation in Obese and Non-Obese Women
چکیده انگلیسی مقاله Background: Obesity is associated with increased lipid peroxidation. It has also been suggested that risk of lipid peroxida­tion increases with increasing body iron stores. The aim of this study was to examine the association of body iron status with the concentration of plasma malondialdehyde (P-MDA) as a marker of lipid peroxidation in obese and non-obese women. Methods: In a case control study we investigated iron status by plasma ferritin, iron and total iron binding capacity (TIBC) meas­urements and lipid peroxidation by plasma malondialdehyde (MDA) levels measurements in 25 obese women and 25 non-obese women matched for age. Results: Plasma ferritin levels were significantly higher in obese groups compared with control groups ( P < 0.001). Plasma TIBC levels were not different in both groups and plasma iron levels were significantly higher in obese groups ( P < 0.05). In obese groups, plasma MDA levels were significantly higher when compared with control groups ( P < 0.001). There were posi­tive correlation between body mass index and plasma MDA levels (r= 0.75, P < 0.0001). Plasma MDA levels were posi­tively correlated with plasma iron levels (r= 0.26, P = 0.001) and plasma ferritin levels (r= 0.39, P < 0.0001) but not with TIBC levels. Conclusion: These findings suggest that obese menstruating women are at low risk of depleting iron stores and hence, increas­ing body iron elevates the CHD risk by promoting the lipid peroxidation. Therefore, iron fortification programs might be undesirable for such subjects. 
کلیدواژه‌های انگلیسی مقاله Iron status, Lipid peroxidation, Women, Obesity
نویسندگان مقاله f امیرخیزی | f amirkhizi
dept. of nutrition and biochemistry, school of public health, tehran university of medical sciences,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

f سیاسی | f siassi
dept. of nutrition and biochemistry, school of public health, tehran university of medical sciences,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

s مینایی | s minaie
dept. of nutrition and biochemistry, school of public health, tehran university of medical sciences,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

جلالی | m djalali
dept. of nutrition and biochemistry, school of public health, tehran university of medical sciences,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

دکتر عباس | a rahimi
dept. of epidemiology and biostatistics, school of public health, tehran university of medical scien

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

چمری | m chamari
dept. of nutrition and biochemistry, school of public health, tehran university of medical sciences,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/2021
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