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Iranian Journal of Public Health، جلد ۳۶، شماره ۳، صفحات ۲۷-۳۲
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عنوان انگلیسی Etiology and Antimicrobial Susceptibility of Bace­rial Septic Arthritis and Osteomyelitis
چکیده انگلیسی مقاله Background: To assess the distribution and resistance of the pathogens responsible for septic arthritis and osteomyelitis over a 10 years period in children admitted to Children's Medical Center Hospital, Tehran, Iran. Methods: Microbiologic and clinical presentation reports from 145 cases of septic arthritis and osteomyelitis from March 1995 to February 2005 were retrospectively reviewed. Results: Of 145 cases, 71(49%) had positive culture: 71.8%(51/71) of organisms were isolated from synovial fluid alone, 8.4%(6/71) from blood culture alone and 19.7% (14/71) from both synovial fluids and blood cultures. Staphylococcus aureus was the most common pathogen isolated, making up 60.5% of all positive cultures, followed by Klebsiella spp. (14%) and coagulase-negative staphylococci (8.4%). Thirty eight percent of S. aureus and 84% of coagulase-negative staphylo­cocci isolates were resistant to cloxacillin. All isolates of S. aureus were susceptible to clindamycin and also, 89% were susceptible to vancomycin. Among Klebsiella spp., amikacin was shown to be very effective, with susceptibility rates of 100%. Haemophilus influenzae was identified in only 2% of all patients. Conclusion: The present study highlights the importance of characterizing the etiology and antibiotic susceptibility of organ­isms causing septic arthritis or osteomylitis in children.
کلیدواژه‌های انگلیسی مقاله Antimicrobial agents, Aarthritis septic
نویسندگان مقاله n کلانتری | n kalantari


m طاهری کلانی | m taherikalani


n پروانه | n parvaneh


s ممیشی | s mamishi


نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/2102
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