این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Medical Laboratory Journal، جلد ۱۰، شماره ۶، صفحات ۱۴-۲۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Effect of Benzalkonium Chloride on Biofilm of Bacteria Causing Nosocomial Infectionstions
چکیده انگلیسی مقاله ABSTRACT          Background and Objective: Biofilms are community of bacteria that attach to inanimate surfaces or living tissues via production of extracellular polymers and exopolysaccharide matrix. Microbial biofilms on various surfaces of the hospital environment are considered as a reservoir of infection spread. The present study aimed to evaluate the disinfecting effect of benzalkonium chloride on some bacterial isolates causing nosocomial infections.        Methods: First, 13 isolates from four bacteria including Pseudomonas aeruginosa, Staphylococcus aureus, Acinetobacter and Enterobacter were obtained from Microbiology Laboratory of Al-Zahra Hospital in Isfahan, Iran. The samples were transferred to Microbiology Laboratory of Faculty of Veterinary Medicine of Shahrekord University for testing. Evaluation of biofilm formation and determination of minimum inhibitory concentration (MIC) of the disinfectant and effect of the disinfectant on planktonic growth and biofilm formation were performed.         Results: All bacterial isolates (52 cases) produced biofilm. Mean MIC of benzalkonium chloride for P. aeruginosa, S. aureus, Enterobacter and Acinetobacter was 0.14, 0.2, 0.18, 0.17 g/ml, respectively. Planktonic growth of all four bacteria was inhibited at concentrations of 2MIC, MIC and 1/2MIC. Biofilm was not produced in MIC and 2MIC concentrations, and biofilm formation capability increased by reducing the concentration of benzalkonium chloride.           Conclusion: The results show that the use of appropriate concentration of benzalkonium chloride can prevent the growth of different bacterial species, but sub-MIC dose of this disinfectant may stimulate biofilm formation.             Keywords: Biofilm, Benzalkonium Chloride, Pseudomonas Aeruginosa, Staphylococcus Aureus, Enterobacter, Acinetobacter.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله عزیزالله ابراهیمی کهریزسنگی | azizollah ebrahimi kahrizsangi
shahrekord university, shahrekord, iran


سعید حبیبیان دهکردی | saied habibian dehkordi
shahrekord university, shahrekord, iran


زیبا شعبان پور | ziba shabanpur
shahrekord university, shahrekord, iran


رضا حکیمی آلنی | reza hakimi alni
bu ali sina university, hamedan, iran

سازمان اصلی تایید شده: دانشگاه بوعلی سینا (Bu ali sina university)

مجید همتی | majid hemati
shahrekord university, shahrekord, iran
نشانی اینترنتی http://goums.ac.ir/mljgoums/browse.php?a_code=A-10-1-430&slc_lang=fa&sid=en
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/168/article-168-448936.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده تخصصی
نوع مقاله منتشر شده تحقیقی
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات