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Iranian Journal of Pediatric Hematology and Oncology، جلد ۷، شماره ۲، صفحات ۱۱۷-۱۲۹
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چکیده فارسی مقاله
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عنوان انگلیسی Genetics of Pediatric Bone Tumors: a Systematic Review
چکیده انگلیسی مقاله Background: Understanding the differences in genetics of malignancies is crucial for therapeutic decisions. This systematic review was conducted to evaluate the current evidence on genetics of bone tumors in the context of pediatric cancer. Material and Methods: We performed a systematic review of the literature published on genetics of pediatrics bone tumors, using PubMed, Google scholar, Science Citation Index and Embase. The search profiles used were: pediatric/childhood malignant bone tumors, pediatric/ childhood bone cancer/neoplasm, osteosarcoma/bone sarcoma/Ewing's sarcoma and risk factors/etiology. Inclusion criteria were as follows: focused upon biology and genetics mechanism of primary bone tumors and published in the last 15 years in English. Results: A total of 278 articles were searched for relevancy, determined by article title, abstract, and full copy. After screening the titles and abstracts, 239 articles were excluded because they were the same articles and case reports. Finally, 39 articles were found that fulfilled all inclusion criteria. Conclusion: This systematic review shows that many genetic studies have been performed on the genetics basis of pediatrics bone tumors. The knowledge base formed by this review should facilitate more informative future research. It is important that orthopedics and other specialists be aware about genetics basis of pediatrics bone tumors.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله محمدرضا سبحان | mohammad reza sobhan
department of orthopedic surgery, shahid sadoughi university of medical sciences, yazd, iran


شادی مصطفوی | shadi mostafavi
school of medicine, shahid sadoughi university of medical sciences, yazd, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید صدوقی یزد (Shahid sadooghi university of medical sciences)

مهتا مظاهری | mahta mazaheri
.department of medical genetics, shahid sadoughi university of medical sciences, yazd, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید صدوقی یزد (Shahid sadooghi university of medical sciences)

حسین نعمت زاده | hossein neamatzadeh
mother and newborn health research center, shahid sadoughi university of medical sciences, yazd, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید صدوقی یزد (Shahid sadooghi university of medical sciences)

نشانی اینترنتی http://ijpho.ssu.ac.ir/browse.php?a_code=A-10-70-123&slc_lang=en&sid=en
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/202/article-202-449169.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده 4
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