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Iranian Journal of Basic Medical Sciences، جلد ۱۷، شماره ۸، صفحات ۵۸۳-۵۸۷
عنوان فارسی
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کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Genetic analysis of two STR loci (VWA and TPOX) in the Iranian province of Khuzestan
چکیده انگلیسی مقاله Objective(s): Short tandem repeat (STR) loci are the most informative DNA genetic markers for attempting to individualize biological material for application in paternity and forensic cases. Materials and Methods: Blood samples were collected and the total genomic DNA was extracted. The DNA samples were used for genotyping VWA and TPOX STR loci using PCR and polyacrylamide gel electrophoresis. Results: This report presents allele frequency data and parameters of biological or legal interest, such as heterozygosity value, polymorphic information content (PIC), genetic diversity index (GD) and population parameter (θ) in Arab and non-Arab population of Khuzestan province (Iran) for the loci VWA and TPOX. Blood samples (N= 392 for VWA and N=308 for TPOX) were collected from individuals unrelated throughout Khuzestan province. The loci were genotyped using the polymerase chain reaction (PCR) followed by polyacrylamide gel electrophoresis (PAGE) and silver staining. Chi-square test showed that neither STR loci were in agreement with the Hardy-Weinberg equilibrium. Conclusion: The examined STR loci in this study have proven a relatively high genetic variation in the Iranian population. The data could be used for construction of a forensic genetic database for the Iranian population.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله علی محمد فروغمند | ali mohammad foroughmand
department of genetics, faculty of science, shahid chamran university of ahvaz, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

مریم جاری | maryam jari
department of genetics, faculty of science, shahid chamran university of ahvaz, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

سید رضا کاظمی نژاد | seyed reza kazeminezhad
department of genetics, faculty of science, shahid chamran university of ahvaz, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

آرزو عبداللهی | arezu abdollahi
department of genetics, faculty of science, shahid chamran university of ahvaz, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

لیلا احمدی | leila ahmadi
department of genetics, faculty of science, shahid chamran university of ahvaz, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

مریم حیدری | maryam heidari
department of genetics, faculty of science, shahid chamran university of ahvaz, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

نشانی اینترنتی http://ijbms.mums.ac.ir/article_3191.html
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زبان مقاله منتشر شده en
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