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Iranian Journal of Basic Medical Sciences، جلد ۱۷، شماره ۴، صفحات ۲۳۷-۲۴۳
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عنوان انگلیسی The effect of eight weeks endurance training and high-fat diet on appetite-regulating hormones in rat plasma
چکیده انگلیسی مقاله Objective(s):Consumption of high-fat foods is one of the major causes of obesity. Physical exercise is a strategy used to counteract obesity. The aim of this study was to investigate the effect of eight weeks endurance training and high-fat diet (HFD) on appetite-regulating hormones in rat plasma. Materials and Methods:Twenty eight male Wistar rats were randomly divided into four groups: Control group with standard diet (CSD), endurance training with a standard diet (ESD), control group with high-fat diet (CHFD) and endurance training with high-fat diet (EHFD). Twenty-four hr after the last training session, the blood samples were obtained and analyzed for hormones levels. Results: The significant increased weight gain and food intake and decreased plasma nesfatin-1 and PYY3-36 levels were observed in CHFD group, while exercise under the HFD antagonized these effects. There were no significant changes in ghrelin, insulin and leptin levels in different groups. Conclusion: These results suggest that exercise can prevent fattening effect of HFD. Probably, performing exercise makes a reduction of food intake and weight gain in rat via the increase in nesfatin-1 and PYY levels. However, further studies are necessary to understand the exact mechanisms involved in this field.
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نویسندگان مقاله روح اله حق شناس | rouhollah haghshenas
department of human science, semnan university, semnan, iran

سازمان اصلی تایید شده: دانشگاه سمنان (Semnan university)

مهوش جعفری | mahvash jafari
exercise physiology research canter, baqiyatallah university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (Baqiyatallah university of medical sciences)

علی اصغر رواسی | aliasghar ravasi
department of exercise physiology, faculty of physical education and sports science, university of tehran, tehran, iran

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

محمدرضا کردی | mohammadreza kordi
department of exercise physiology, faculty of physical education and sports science, university of tehran, tehran, iran

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

ندا گیلانی | neda gilani
department of biostatistics, faculty of medical science, tarbiat modares university, tehran, iran

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

محمد شریعت زاده | mohammad shariatzadeh
sport science and physical education research center, mashhad, iran


مهدی هدایتی | mehdi hedayati
obesity research center, research institute for endocrine sciences, shahid beheshti university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

مصطفی رحیمی | mostafa rahimi
exercise physiology research canter, baqiyatallah university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (Baqiyatallah university of medical sciences)

نشانی اینترنتی http://ijbms.mums.ac.ir/article_2580.html
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