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Iranian Journal of Basic Medical Sciences، جلد ۱۶، شماره ۱۰، صفحات ۱۰۳۱-۱۰۴۸
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چکیده فارسی مقاله
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عنوان انگلیسی Therapeutic Uses and Pharmacological Properties of Garlic, Shallot, and Their Biologically Active Compounds
چکیده انگلیسی مقاله Objective(s): Garlic (Allium sativum L. family Liliaceae) is well known in Iran and its leaves, flowers, and cloves have been used in traditional medicine for a long time. Research in recent decades has shown widespread pharmacological effects of A. sativum and its organosulfur compounds especially Allicin. Studies carried out on the chemical composition of the plant show that the most important constituents of this plant are organosulfur compounds such as allicin, diallyl disulphide, S-allylcysteine, and diallyl trisulfide. Allicin represents one of the most studied among these naturally occurring compounds. In addition to A. sativum, these compounds are also present in A. hirtifolium (shallot) and have been used to treat various diseases. This article reviews the pharmacological effects and traditional uses of A. sativum, A. hirtifolium, and their active constituents to show whether or not they can be further used as potential natural sources for the development of novel drugs. Materials and Methods: For this purpose, the authors went through a vast number of sources and articles and all needed data was gathered. The findings were reviewed and classified on the basis of relevance to the topic and a summary of all effects were reported as tables. Conclusion: Garlic and shallots are safe and rich sources of biologically active compounds with low toxicity. Further studies are needed to confirm the safety and quality of the plants to be used by clinicians as therapeutic agents.
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نویسندگان مقاله پیمان میکاییلی | peyman mikaili
department of pharmacology, faculty of pharmacy, urmia university of medical sciences, urmia, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ارومیه (Urmia university of medical sciences)

سروش maadirad | surush maadirad
urmia university, faculty of veterinary medicine, urmia, iran

سازمان اصلی تایید شده: دانشگاه ارومیه (Urmia university)

میلاد moloudizargari | milad moloudizargari
urmia university, faculty of veterinary medicine, urmia, iran

سازمان اصلی تایید شده: دانشگاه ارومیه (Urmia university)

شاهین aghajanshakeri | shahin aghajanshakeri
urmia university, faculty of veterinary medicine, urmia, iran

سازمان اصلی تایید شده: دانشگاه ارومیه (Urmia university)

شادی سرهرودی | shadi sarahroodi
department of physiology and pharmacology, school of medicine, qom university of medical sciences, qom, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی قم (Qom university of medical sciences)

نشانی اینترنتی http://ijbms.mums.ac.ir/article_1865.html
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Review Article
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