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Iranian Journal of Basic Medical Sciences، جلد ۱۵، شماره ۱، صفحات ۶۷۸-۶۸۲
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عنوان انگلیسی Prevalence of PER-1- type Extended-Spectrum Beta-Lactamaes in Clinical Strains of Pseudomonas aeruginosa Isolated from Tabriz, Iran
چکیده انگلیسی مقاله Objective(s) The aim of this study was to investigate the presence of PER-1-type ESBLs in drug resistant Pseudomonas aeruginosa isolates. Materials and Methods During one-year period (2008-2009), following isolation and identification of 56 P. aeruginosa, the E-test method was performed for determination of minimal inhibitory concentration of ceftazidim. The isolates that they had MIC≥16 µg/ml against ceftazidim were used for determination of ESBL-producing by combined disk test (CDT) and double disk synergy test (DDST) methods. Bla PER-1genewas investigated by PCR.P. aeruginosa KOAS was used as positive control. Results Twenty-nine (51.78%) out of fifty six isolates had MIC≥16 µg/ml to ceftazidime, twenty two (75.86%) of them were ESBL producers. Some isolates (27.5%) contained bla PER-1 gene. Conclusion PER-1-type ESBLs producing P.aeruginosa has not been reported previously in Tabriz but there has been a rather high prevalence of it.
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نویسندگان مقاله محمد تقی اخی | mohammad taghi akhi
department of microbiology, faculty of medicine, and research center of infectious diseases and tropical medicine, tabriz university of medical sciences, tabriz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

یونس خلیلی | yones khalili
department of microbiology, faculty of medicine, and research center of infectious diseases and tropical medicine, tabriz university of medical sciences, tabriz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

رضا ghottaslou | reza ghottaslou
department of microbiology, faculty of medicine, and research center of infectious diseases and tropical medicine, tabriz university of medical sciences, tabriz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

محمد آقازاده | mohammad aghazadeh
department of microbiology, faculty of medicine, and research center of infectious diseases and tropical medicine, tabriz university of medical sciences, tabriz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

محمد حسین seroush bar حقی | mohammad hosein seroush bar haghi
department of microbiology, faculty of medicine, and research center of infectious diseases and tropical medicine, tabriz university of medical sciences, tabriz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

صابر یوسفی | saber yousefi
department of clinical laboratory sciences, faculty of paramedicine, urmia university of medical science

سازمان اصلی تایید شده: دانشگاه ارومیه (Urmia university)

نشانی اینترنتی http://ijbms.mums.ac.ir/article_4837.html
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