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Iranian Journal of Basic Medical Sciences، جلد ۱۴، شماره ۵، صفحات ۴۵۸-۴۶۴
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چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی qnr Prevalence in Extended Spectrum Beta-lactamases (ESBLs) and None- ESBLs Producing Escherichia coli Isolated from Urinary Tract Infections in Central of Iran
چکیده انگلیسی مقاله Objective(s) Extensive use of quinolones has been associated with raising level of resistance. In the current, we focused on assessing the prevalence of Escherichia coli resistance to quinolones and frequency of qnrA, qnrB and qnrS in non ESBLs (extended spectrum beta-lactamases) and ESBLs producing E. coli with blaSHV and blaTEM. Materials and Methods One hundred and fifty E. coli isolates were identified during Mar. 2007 to Apr. 2008 in Milad (Tehran) hospital. They were tested for ESBLs production as well as quinolone resistance. PCR was performed for detection of blaSHV and blaTEM as well as qnrA, B and S. Results Of 150 isolates, forty-two (28%) ESBLs producing and one hundred and eight (72%) non-ESBLs producing E. coli were identified. 64.2% (n= 24) of E. coli producing ESBLs and 4.62% (n= 5) of non-ESBLs E. coli were resistance to ciprofloxacin. 95.2% (n= 40) and 26.1% (n= 11) of the isolates harbored blaTEM and blaSHV, respectively. 23.8% (n= 10) had both genes. 37.5% (n= 9) and 20.8% (n= 4) of ESBLs producing E. coli were positive for qnrA and qnrB respectively. qnrS was not identified in any isolate. Conclusion Our study showed high frequency of ESBLs producing E. coli as well as quinolone resistance genes (qnrA, qnrB) in Milad hospital.
کلیدواژه‌های انگلیسی مقاله Ciprofloxacin, Iran, Resistance
نویسندگان مقاله ایرج پاکزاد | iraj pakzad
department microbiology, faculty of medicine and clinical microbiology research center, ilam university of medical sciences, ilam, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)

sohbhan غفوریان | sohbhan ghafourian
department microbiology, faculty of medicine and clinical microbiology research center, ilam university of medical sciences, ilam, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)

مروت طاهری کلانی | morovat taherikalani
department microbiology, faculty of medicine and clinical microbiology research center, ilam university of medical sciences, ilam, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)

نورخدا صادقی فرد | norkhoda sadeghifard
department microbiology, faculty of medicine and clinical microbiology research center, ilam university of medical sciences, ilam, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایلام (Ilam university of medical sciences)

حمید ابطحی | hamid abtahi
department microbiology, faculty of medicine and molecular medicine research center, arak university of medical sciences, arak, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (Arak university of medical sciences)

محمد رهبر | mohammad rahbar
department microbiology, iranian reference health laboratory, tehran, iran


ندا منصوری | neda mansory jamshidi
department microbiology, karaj islamic azad university, karaj iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

نشانی اینترنتی http://ijbms.mums.ac.ir/article_5042.html
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