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Iranian Journal of Basic Medical Sciences، جلد ۱۲، شماره ۲، صفحات ۱۰۵-۱۱۱
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Antibacterial Activity of Twenty Iranian Plant Extracts Against Clinical Isolates of Helicobacter pylori
چکیده انگلیسی مقاله Objective(s) Due to increasing emergence of drug-resistance in Helicobacter pylori isolates, traditional plants are potentially valuable sources of novel anti-H. pylori agents. In this research, anti-H. pylori activity of the organic extracts of twenty native Iranian plants was determined against ten clinical isolates of H. pylori. Materials and Methods Disc diffusion was used to determine the biological activity of 20 plant extracts as well as 8 antibiotics commonly used to treat H. pylori infections. Minimum inhibitory concentrations were also measured by tube and agar dilution methods for the biologically active plant extracts. Results Of the twenty plant extracts analyzed, sixteen exhibited good anti-H. pylori activity, using disc diffusion. The ten most active extracts were Carum bulbocastanum, Carum carvi, Mentha longifolia, Saliva limbata, Saliva sclarea, Ziziphora clinopodioides, Thymus caramanicus, Glycyrrhiza glabra, Xanthium brasilicum and Trachyspermum copticum. Minimum inhibitory concentrations measured for the 10 biologically active plant extracts were within the range of 31.25 to 500 ^g/ml. Conclusion Among the ten plant extracts effective against H. pylori clinical isolates, Carum carvi, Xanthium brasilicum and Trachyspermum copticum showed the highest activity.
کلیدواژه‌های انگلیسی مقاله Anti-Helicobacter pylori, Iranian plants, Organic extracts
نویسندگان مقاله فرحناز نریمان | farahnaz nariman
department of biology and microbiology, faculty of sciences, alzahra university, tehran, iran

سازمان اصلی تایید شده: دانشگاه الزهرا (Alzahra university)

فرشته افتخار | fereshteh eftekhar
department of microbiology, faculty of biological sciences, shahid beheshti university, g.c., tehran, iran

سازمان اصلی تایید شده: دانشگاه شهید بهشتی (Shahid beheshti university)

زهره حبیبی | zohreh habibi
department of chemistry, faculty of sciences, shahid beheshti university, g.c., tehran, iran

سازمان اصلی تایید شده: دانشگاه شهید بهشتی (Shahid beheshti university)

صادق massarrat | sadegh massarrat
digestive diseases research center, faculty of medical sciences, tehran university, tehran, iran

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

رضا ملک زاده | reza malekzadeh
digestive diseases research center, faculty of medical sciences, tehran university, tehran, iran

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

نشانی اینترنتی http://ijbms.mums.ac.ir/article_5151.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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