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فصلنامه علمی پژوهشی گیاهان دارویی، جلد ۳، شماره ۳۱، صفحات ۸۷-۹۲
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عنوان انگلیسی Effects of Danae racemosa on Spermatogenesis in Rat
چکیده انگلیسی مقاله Background: Danae racemosa is used medicinally and as a culinary spice. Its constituents are stated to have antithrombotic, antihepatotoxic, antinociceptive and antioxidant. Objective: Enhanced oxidative stress and changes in antioxidant capacity are considered to play an important role in the pathogenesis of chronic diabetes mellitus. Methods: Wistar male rat (n=30) were allocated into three groups, control (n=10) and two test groups (each of ten). Animals in test groups were subdivided into groups of 2 that received fresh extract equivalent to 200 & 400 mg/Kg/Rat/day Danae racemosa extract. Fresh Danae racemosa extract was administered with gavages for 28 consecutive days. Animals were kept in standard condition. On twenty eighth day, the testes of rats in the all groups were removed and sperm was collected from epididymis and was prepared for analysis. Results: The percentage of sperm viability and motility in both test groups significantly increased (p< 0.05), but the sperm concentration significantly increased only in the group that received the high dose of Danae racemosa extracted, (p< 0.05). It was evident that there was no difference on sperm morphology and testis weight in test groups comparing to control group. Conclusion: In our study Danae racemosa extract has significantly affected the sperm number and percentage of viability and motility it seems that using 400 mg/Kg/Rat/day of Danae racemosa extract is effective in sperm health parameters.
کلیدواژه‌های انگلیسی مقاله Danae racemosa, Extract, Sperm, Rat
نویسندگان مقاله a خاکی | a khaki
no. 1 ettekali la, south shariati street, 5138815941, tabriz, iran mobile phone 98-9143138-399


f فتحی آزاد | f fathiazad
department of pharmacognosy tabriz university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

hr احمدی آشتیانی | hr ahmadi ashtiani
department of clinical biochemistry, school of medical science, tarbiat modarres university, tehran, iran; biochemistry amp;amp; nutrition department of zanjan medical university

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

h رستگار | h rastgar
ministry of health and medical education, food amp;amp; drug laboratory research center

سازمان اصلی تایید شده: وزارت بهداشت درمان و آموزش پزشکی (Ministry of health and medical education)

sh رضازاده | sh rezazadeh
institute of medicinal plants, acecr

سازمان اصلی تایید شده: پژوهشکده‮ ‬گیاهان‮ ‬دارویی‮ ‬جهاد‮ ‬دانشگاهی (Institute of medicinal plants)

نشانی اینترنتی http://www.jmp.ir/browse.php?a_code=A-10-176-7&slc_lang=en&sid=fa
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده کلینیکال پاتولوژی
نوع مقاله منتشر شده پژوهشی
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