این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Microbiology، جلد ۷، شماره ۴، صفحات ۲۰۳-۲۰۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Prevalence of the bla CTX-M group and their transferability in resistant clinical isolates of Salmonella serogroups from several hospitals of Tehran
چکیده انگلیسی مقاله Background and Objectives: Salmonella is an important food-borne pathogen in humans. Strains of Salmonella spp. That producing extended-spectrum β-Lactamases have become a concern in medicine regarding both antimicrobial treatment and infection control program. The objective of this study was to describe the antibiotic susceptibility, ESBL production and determining the prevalence of the bla CTX-M-1 group among clinical isolates of Salmonella spp. Materials and Methods: A total of 110 Salmonella isolates collected from four Tehran hospitals during May 2012 and April 2013. The specific monovalan Salmonella antisera were used for serogrouping of Salmonella isolates. Antibacterial susceptibility was determined by disk diffusion and ESBL phenotype was confirmed by combination disk method. The bla CTX-M-1 group was identified by PCR with specific primers. The transferability of the bla CTX-1 group was tested by conjugation with broth matting method. Results: The prevalence of Salmonella serogroups consist of 56.4% serogroup D, 13.6 % serogroup C, 10 % serogroup B, and 1.8 % serogroup A and 18.2% other serogroups. Maximal resistance in Salmonella isolates was noticed against trimethoprim-sulfamethoxazole (63.6%) and nalidixic-acid (47/3%). All isolates were susceptible to imipenem and ciprofloxacin. Four isolates (3.6%) showed ESBLs phenotype. All Salmonella spp. that produce ESBls have bla CTX-1 genes group. A conjugative plasmid containing bla CTX-1 group was found in one Salmonella isolate. Conclusion: This study demonstrates the predominant presence of the gene encoding CTX-M-1 group among ESBLs producing of Salmonella spp. They can transmit to bacteria of this genus or even other genera of enteric bacteria.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله کبری سلیمیان ریزی | kobra salimian rizi
department of bacteriology, faculty of medical sciences, tarbiat modares university, teheceivedran, ir iran.

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

شاهین نجار پیرایه | shahin najar peerayeh
department of bacteriology, faculty of medical sciences, tarbiat modares university, teheceivedran, ir iran.

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

بیتا بخشی | bita bakhshi
department of bacteriology, faculty of medical sciences, tarbiat modares university, teheceivedran, ir iran.

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

دکتر محمد رهبر | mohammad rahbar
department of microbiology, reference health laboratories research center, deputy of health, ministry of health and medical education, tehran, iran.

سازمان اصلی تایید شده: وزارت بهداشت درمان و آموزش پزشکی (Ministry of health and medical education)

نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/128
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Articles
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات