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Iranian Journal of Microbiology، جلد ۶، شماره ۲، صفحات ۸۴-۸۶
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عنوان انگلیسی Invasive community-acquired Staphylococcus aureus among pediatric population of Eastern Iran.
چکیده انگلیسی مقاله Background and Objective: Community-acquired methicillin-resistant Staphylococcus aureus ( CA-MRSA) is increasingly reported worldwide. We aimed to determine the frequency of invasive CA-MRSA in children admitted to the pediatric wards of Imam Reza and Ghaem hospitals of Mashhad, Iran. Materials and Methods: In this retrospective study, data regarding S. aureus isolates from pediatric patients’ sterile body sites (i.e. blood‚ joint, bone and lymph node aspiration) were retrieved in a time period from March 2006 to March 2012. Disc diffusion data was analyzed to determine the resistance pattern of the isolates, and differentiation between community- acquired and nosocomial S. aureus was done according to CDC guidelines. Results: Twenty three invasive community-acquired S. aureus isolates from sterile body sites were identified, of which seventeen (74%) were CA-MRSA. The CA-MRSA isolates showed high frequency of resistance to non-β-lactam antibiotics (71% to erythromycin‚ 53% to co-trimoxazole, 44% to gentamicin and 36% to ciprofloxacin). Conclusion: In this study, the majority of invasive community-acquired S. aureus isolates were found to be CA-MRSA. Therefore, we recommend that primary treatment should be with antibiotics such as clindamycin, vancomycin, linezolid or daptomycin for any invasive infection suspected to be caused by S. aureus in these two hospitals.
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نویسندگان مقاله محمدسعید ساسان | mohammadsaeed sasan
department of pediatrics, mashhad university of medical sciences, mashhad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

ناهید دنیادیده | nahid donyadide
department of pediatrics, mashhad university of medical sciences, mashhad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

عمران عسکری | emran askari
students research committee, mashhad university of medical sciences, mashhad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

محبوبه نادری نسب | mahboobeh naderi nasab
department of microbiology, central laboratory, imam reza teaching hospital, mashhad university of medical sciences, mashhad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/447
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