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Iranian Journal of Microbiology، جلد ۵، شماره ۱، صفحات ۲۴-۲۷
عنوان فارسی
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کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Low Prevalence of Brucella agglutinins in Blood Donors in Central Province of Iran.
چکیده انگلیسی مقاله Background and Objective: Brucellosis is a zoonotic disease of worldwide distribution and has great economic importance. Despite its control in many countries, it remains endemic in Iran. Brucellosis was investigated in many high risk occupational groups; however, few studies on the prevalence of brucellosis among blood donors are available. To determine the seroprevalence of brucellosis antibodies in blood donors, a serological study was carried out in central province of Iran. Materials and Methods: A total of 897 healthy blood donors with mean age 37.23 ± 10.9 years were enrolled in the study. Laboratory tests including Standard Tube Agglutination Test (STA) and 2-mercaptoethanol (2ME) agglutination were checked in all samples. STA dilution ≥ 1:80, and in the presence of 2-mercaptoethanol (2ME) agglutination ≥ 20 was considered positive. Results: Out of 897 cases, 11.9% were inhabitants of rural areas. 41.5% had history of consumption of unpasteurized dairy products and 9.3% had history of contact with domestic animals. A very low level of Brucella agglutinins was present in 3(0.33%) of the samples and only one sample (0.11%) was found to be truly positive for Brucella agglutinins. 2ME was negative in all samples. None of these 4 subjects showed signs and symptoms of brucellosis in 6 months follow-up. Conclusion : On the basis of our data, brucellosis has no epidemiological and clinical importance in our blood donors; therefore, it is not recommended to perform screening tests such as, STA and 2ME to identify brucellosis antibodies in the sera of blood donors.
کلیدواژه‌های انگلیسی مقاله Brucella agglutinins,Brucellosis,blood donors
نویسندگان مقاله معصومه صوفیان | masoomeh sofian
tuberculosis and pediatric infectious research center, arak university of medical sciences, arak, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (Arak university of medical sciences)

مهرنوش شیخ الاسلامی | mehrnoosh sheikholeslami
arak university of medical sciences, arak, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (Arak university of medical sciences)

فاطمه السادات مهدویانی | fatemeh alsadat mahdaviani
blood transfusion organization research center, advanced institute for research and education in transfusion medicine, tehran, iran.

سازمان اصلی تایید شده: سازمان انتقال خون ایران (Blood transfusion research center)

آرزو آقاخانی | arezoo aghakhani
clinical research dept., pasteur institute of iran, tehran, iran.

سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

محمد بنی فضل | mohammad banifazl
iranian society for support of patients with infectious disease, tehran, iran.


علی اسلامی فر | ali eslamifar
clinical research dept., pasteur institute of iran, tehran, iran.

سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

حسین سرمدیان | hossein sarmadian
tuberculosis and pediatric infectious research center, arak university of medical sciences, arak, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (Arak university of medical sciences)

قربان دیری | ghorban deiri
blood transfusion organization research center, advanced institute for research and education in transfusion medicine, tehran, iran.

سازمان اصلی تایید شده: سازمان انتقال خون ایران (Blood transfusion research center)

آمیتیس رمضانی | amitis ramezani
clinical research dept., pasteur institute of iran, tehran, iran.

سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/657
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