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Iranian Journal of Microbiology، جلد ۴، شماره ۳، صفحات ۱۳۰-۱۳۵

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عنوان انگلیسی Capsular serotype and antibiotic resistance of group B streptococci isolated from pregnant women in Ardabil, Iran.
چکیده انگلیسی مقاله Background and Objectives: Group B Streptococci (GBS) is a major cause of neonatal and maternal infections. The aim of this study was to determine the serotype distribution and antibiotic resistance profile of GBS strains isolated from pregnant women in Ardabil. Materials and Methods: Antibiotic resistance of 56 GBS isolates was investigated using E-test strips and disk-diffusion method. Serotyping was performed using capsular antiserum. Results: The results of MIC tests showed all isolates were susceptible to ampicillin, vancomycin and penicillin. One isolate (1.7%) showed reduced susceptibility pattern to penicillin (MIC; 0.25 µg/ml). There were 3 (5.3%) isolates semi-sensitive (0.25-1 µg/ml) to erythromycin (2; 0.5 µg/ml and 1; 0.38 µg/ml) and 2 (3.5%) isolates to clindamycin (1; 0.5 µg/ml, 1;0.38 µg/ml). Additionally, 2 (3.5%) isolates were resistant to clindamycin (1; 16 µg/ml, 1; 2 µg/ml). According to the disk diffusion test, 47 (83.9%), 8 (14.2%) and 7 (12.5%) isolates were resistant to Co-trimoxazole, ciprofloxacin and ceftriaxone respectively. Serotypes V (19.6%), II (12.5%) and IV (12.5%) were the most frequent followed by serotypes III (10.7%) and VI (10.7%), Ib (8.9%), Ia (7/1%), VII (5/3%) and VIII (5/3%); 7.1% of strains were nontypeable. Conclusions: In this study, most isolates were sensitive to common antibiotics, but increased resistance to other antibiotics indicates the importance of monitoring of antibiotic resistance in group B streptococci over time.
کلیدواژه‌های انگلیسی مقاله Antibiotic resistance,Group B Streptococci,Serotype

نویسندگان مقاله e جنتی | e jannati
department of microbiology, school of sciences, ardabil branch, islamic azad university, ardabil, iran.

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

m روشنی | m roshani
general practitioner, ardabil university of medical sciences, ardabil, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اردبیل (Ardabil university of medical sciences)

ارزنلو | m arzanlou
department of microbiology, school of medicine, ardabil university of medical sciences, ardabil, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اردبیل (Ardabil university of medical sciences)

حبیب زاده | s habibzadeh
department of infectious diseases, school of medicine, ardabil university of medical sciences, ardabil, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اردبیل (Ardabil university of medical sciences)

g رحیمی | g rahimi
department of obstetrics and gynecology, school of medicine, ardabil university of medical sciences, ardabil, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اردبیل (Ardabil university of medical sciences)

r شاپوری | r shapuri
biology research center, zanjan branch, islamic azad university, zanjan, iran.

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)


نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/698
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