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Asia Pacific Journal of Medical Toxicology، جلد ۶، شماره ۲، صفحات ۵۵-۵۸
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عنوان انگلیسی Do Opium Abusers Develop Lead Toxicity? A Study on Opium Abusers in Hamadan, Iran
چکیده انگلیسی مقاله Background:Raw opium is a kind of drug, abused a lot in Iran. In a vast majority of cases, various impurities including lead are added to raw opium. This study aimed to evaluate Blood Lead Level (BLL) and probable clinical symptoms triggered by it among opium abusers. Methods:This study was case control and conducted on 40 patients addicted to raw opium (case group) and 40 patients without any kind of addiction (control group) who were hospitalized in the poisoning ward of Farshchian hospital, Hamadan, Iran. BLL was measured by Atomic Absorption Spectroscopy (AAS) and compared between the two groups. Para clinical tests and peripheral blood smear were also assessed to check basophilic erythrocytes. Results: The patients' mean age was 51.9±15.8 years in the control group and 53.2±15 years in the case   group. Besides, the mean of BLL was 4.02±3.16 µg/dl in the control group and 22.41±21.14 µg/dl in the case group, and the difference was statistically significant (p< 0.001). Moreover, routes of exposure included inhalation (72.5%), oral (12.5%), and both (15%). The results indicated no significant associations between the route of exposure and BLL (p< 0.281).Furthermore, no special clinical symptoms were observed in most patients in both groups. Nonetheless, anemia and basophilic erythrocytes were detected in 3 patients who had high BLL. Conclusion:With regard to the high BLL in raw opium abuser, it seems that poisoning with lead should be considered if patients with a history of raw opium addiction refer to physicians. 
کلیدواژه‌های انگلیسی مقاله Addiction, Blood Lead level, Opium
نویسندگان مقاله سعید افضلی | saeed afzali
behavioral disorders and substance abuse center of hamadan university of medical sciences, hamadan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

سعادت ترابیان | saadat torabian
research assistant university health network toronto general hospital, toronto.,ontario


سید کاظم طاهری | seyed kazem taheri
department of forensic medicine and toxicology, school of medicine, hamadan university of medical sciences, hamadan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

نشانی اینترنتی http://apjmt.mums.ac.ir/article_8951.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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