این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Chemistry and Chemical Engineering، جلد ۳۶، شماره ۳، صفحات ۱۱۵-۱۲۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Solid Phase Extraction Using Modified Magnetic Iron Oxide Nanoparticles for Extraction and Spectrofluorimetric Determination of Carvedilol in Human Plasma Samples
چکیده انگلیسی مقاله A new analytical approach was developed involving magnetic solid–phase extraction and spectrofluorimetric determination of carvedilol in human plasma samples. A plasma sample was prepared and adjusted to pH 8.2–10, then carvedilol was quickly extracted using iron oxide magnetic nanoparticles modified by the surfactant cetyltrimethylammonium bromide and determined to apply spectrofluorimetry at 354 ± 3 nm after excitation at 241 ± 3 nm. Experimental conditions, such as the amount of nanoparticles and cetyltrimethylammonium bromide, pH value, standing time and desorption solvent type and volume have been adjusted to optimize the extraction process and to obtain analytical characteristics of the method. Linearity was observed in the analyte concentration range of 2.0–125 ng/mL with correlation coefficients (r) of 0.999. The method showed good precision and accuracy, with intra– and inter–assay precisions of less than 7.0% at all concentrations. Standard addition recovery tests were carried out, and the recoveries ranged from 94.4% to 100.7%. The limits of detection and quantification were found to be 0.67 and 2.24 ng/mL. The method was applied to the determination of carvedilol in human plasma samples. 
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله احد باویلی تبریزی | bavili tabrizi
biotechnology research center, tabriz university of medical sciences, tabriz, i.r. iran department of medicinal chemistry, faculty of pharmacy, tabriz university of medical sciences, tabriz. i.r. iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

مهدی پناهی |
drug applied research center, tabriz university of medical sciences, tabriz, i.r. iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

نشانی اینترنتی http://www.ijcce.ac.ir/article_28069_1066266fb6c8021ee9321dca83efd491.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/444/article-444-485041.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات