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Iranian Journal of Toxicology، جلد ۱۱، شماره ۶، صفحات ۴۳-۴۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Response of Melanomacrophage Centers in Yellowfin Seabream (Acanthopagrus latus) Immune Organs as an Immunohistological Biomarker in Short-term Exposure to Phenanthrene
چکیده انگلیسی مقاله Background: The aim of this study was to assess the changes in plasma levels of antioxidant enzymes and melano-macrophage centers (MMCs) in immune tissues as biomarkers of yellowfin seabream (Acanthopagrus latus) exposed to phenanthrene (Phe) for 14 days. Methods: The research was carried out at Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran in Jan 2016. Thirty-six immature fish were intraperitoneally injected with coconut oil (10 μl/g-bw) containing Phe (70mg/kg-bw) and compared with control group (without injection). Then tissue and blood samples were obtained at 1, 4, 7 and 14 d after injection. Results: The SOD and CAT activity showed a significant decrease in fish exposed to Phe up to day 7, then activity increased at day 14 in Phe-treated fish (P< 0.05). The size and number of MMCs in treated fish in spleen and head kidney were higher than control. Conclusion: Changes in these parameters (SOD, CAT, and MMCs) might be used as useful biomarkers for evaluating immunosuppressive Phe in fish.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله مهرناز شیرمحمدی | mehrnaz shirmohammadi
department of marine biology, faculty of marine science, khorramshahr university of marine science and technology, khorramshahr, iran.


محمد تقی رونق | mohammad taghi ronagh
department of marine biology, faculty of marine science, khorramshahr university of marine science and technology, khorramshahr, iran.


نگین سلامت | negin salamat
department of marine biology, faculty of marine science, khorramshahr university of marine science and technology, khorramshahr, iran.


عبدالعلی موحدی نیا | abdolali movahedinia
department of marine biology, faculty of marine science, khorramshahr university of marine science and technology, khorramshahr, iran.


غلامرضا حمیدیان | gholamreza hamidian
department of basic sciences, faculty of veterinary medicine, university of tabriz, tabriz, iran.

سازمان اصلی تایید شده: دانشگاه تبریز (Tabriz university)

نشانی اینترنتی http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-446-2&slc_lang=en&sid=en
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زبان مقاله منتشر شده en
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