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JCR 2016
جستجوی مقالات
جمعه 21 آذر 1404
Iranian Journal of Blood and Cancer
، جلد ۳، شماره ۴، صفحات ۴۵-۴۹
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Relation between the Short Term Health Related Quality of Life and Various Types of Medical Treatment in Patients with Idiopathic Chronic Thrombocytopenia
چکیده انگلیسی مقاله
Background:Chronic Idiopathic Thrombocytopenic Purpura (ITP) is an autoimmune disorder characterized by a low platelet count due to reduced production and higher destruction of the platelets. Therapy is aimed at increasing the patient’s platelet count to safe levels and includes a wide variety of treatments, which has a large impact on the patient’s quality of life. Health Related Quality of Life (HRQoL) is one of the most important factors to evaluate the efficacy of the treatment. This study was conducted to compare the effect of the various types of treatment on HRQoL in ITP patients. Materials and Methods:Ninety under 25 year-old patients were included in this cross-sectional study. All patients had active disease with platelet count of less than 120,000/mm3. The patients were divided into 3 treatment groups: 1- Intravenous immunoglobulin (IVIg) treatment, 2- various corticosteroids treatments and 3- Immunosuppressive treatments, and filled-out a validated “quality of life” questionnaire.The HRQoL was calculated according to the collected information such as well-physical activity, gynecologic problems, bleeding disorders, response to treatment, side effects and social interactions. Results:Ninety patients were enrolled, consisting of 38 male and 52 females. The mean age of the patients was 19.73±4.02 years. The mean total score of HRQoL was 21.8±9.1. We did not find any significant difference in HRQoL total score among treatment groups (p=0.129). Conclusion: HLQoL did not differ among treatment protocols and it seems that other factors are more important in influencing quality of life among ITP patients. Keywords: Purpura, thrombocytopenic, idiopathic, quality of life, immunoglobulins, corticosteroids, immunosuppressive agent
کلیدواژههای انگلیسی مقاله
نویسندگان مقاله
m فرانوش | m faranoush
associate professor of pediatric hematology oncology, rassool- akram hospital , iranian blood transfusion organization
سازمان اصلی تایید شده
: سازمان انتقال خون ایران (Blood transfusion research center)
kh ارجمندی رفسنجانی | kh arjmandi rafsanjani
associate professor of pediatric hematology oncology, ali asghar children’s hospital ,tehran university of medical sci
سازمان اصلی تایید شده
: دانشگاه تهران (Tehran university)
z صدر | z sadr
pediatrician, ali asghar children’s hospital , tehran university of medical sciences
سازمان اصلی تایید شده
: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
aa هدایتی اصل | aa hedayatiasl
associate professor of pediatric hematology oncology, mahak children’s hospital,tehran, iran
سازمان اصلی تایید شده
: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
a مهرور | a mehrvar
associate professor of pediatric hematology oncology, mahak children’s hospital,tehran, iran
نشانی اینترنتی
http://www.ijbc.ir/browse.php?a_code=A-10-1-16&slc_lang=en&sid=en
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en
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