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Iranian Journal of Blood and Cancer، جلد ۲، شماره ۴، صفحات ۰-۰
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عنوان انگلیسی Neonatal Screening for Sickle Cell Disease in South West Iran: a Pilot Study
چکیده انگلیسی مقاله Background: Children affected with sickle cell disease (SCD) are at increased risk for severe morbidity and mortality, especially during the first 3-5 years of life. It is suggested that early treatment can improve the condition. The aim of this pilot study was to estimate the incidence of hemoglobin S (HbS) by umbilical cord blood screening in Khorramshahr and Abadan cities in southwest of Iran. Materials and Methods: Cord blood sample (10 ml) was collected and stored in ethylenediaminetetraacetic acid (EDTA) precoated tubes and transported to the reference laboratory in Ahwaz. Samples were analyzed for presence of HbS by hemoglobin electrophoresis. Positive specimens were confirmed by sickle preparation test. Results: Four patients (1.3%) with sickle cell disease were identified among 308 screened newborns, all with Arabian ethnic origin. Conclusion: We concluded that HbS is a common disease in Khuzestan Province.
کلیدواژه‌های انگلیسی مقاله Sickle cell anemia, Neonatal screening, Iran.
نویسندگان مقاله علی احمدزاده | ali ahmadzadeh
abuzar children’s hospital, ahwaz jondishpour university of medical sciences, ahvaz, iran.


masstaneh مقتدری | masstaneh moghtaderi
abuzar children’s hospital, ahwaz jondishpour university of medical sciences, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

خدامراد زندیان | khodamorad zandian
research center for thalassemia and hemoglobinopathies, jondishapour university of medical sciences, ahwaz, iran
نشانی اینترنتی http://www.ijbc.ir/browse.php?a_code=A-10-2-235&slc_lang=en&sid=en
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