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مجله پزشکی ارومیه، جلد ۲۸، شماره ۸، صفحات ۴۲-۴۸

عنوان فارسی Platelet counts and its course for predicting in-hospital mortality in intensive care unit
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عنوان انگلیسی Platelet counts and its course for predicting in-hospital mortality in intensive care unit
چکیده انگلیسی مقاله Background & Aims: Recent studies have shown that thrombocytopenia (TP) is associated with poor outcomes in patients with pneumonia, burns, and H1N1 influenza. The aim of this study is to determine the impact of platelet count trends and TP on mortality in intensive care unit (ICU) patients. Materials & Methods: TP was defined as < 150,000 platelets/ml. In this study, 300 patients who had been admitted to the ICU for internal diseases were evaluated for platelet counts on the day of admission and following days to assess the presence of TP. Comparisons were made between patients who died in the ICU and those who were discharged for presence of TP, mean platelet counts, and changes in platelet counts. Platelet count trends were evaluated with repeated measurement tests. P < 0.05 was significant. Results: Of 300 patients, 131 (43.7%) had TP upon admission to the ICU. The rates of TP were 60% among patients who died as compared to 34% among surviving patients (p < 0.001, risk ratio = 3.07, 95% CI 1.88–5.01). Mean platelet counts on admission day and all four of the following days were significantly lower in patients who died than patients who survived (p < 0.001). On the days after admission, platelet counts tended to increase in surviving patients and decreased among non-surviving patients. Conclusion: TP is commonly observed in ICU patients. TP diagnosis and trends of decreasing platelet counts over time are each predictors of mortality among ICU patients. Because platelet counts are inexpensive and readily available, our findings suggest that their use helps inform clinical decision-making in patients with critical illness.
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نویسندگان مقاله محمد حسین رحیمی راد | mohammad hossein rahimi rad
department of internal medicine, pulmonologist, full professor of urmia university of medical sciences, urmia, iran
urmia university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ارومیه (Urmia university of medical sciences)

محمد امین ولیزاد حسنلویی | mohammad amin valizade hasanloei
department of anesthesiology, fellow ship of intensive care medicine, associate professor of urmia university of medical sciences, urmia, iran
department of internal medicine, pulmonologist, full professor of urmia university of medical sciences, urmia, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ارومیه (Urmia university of medical sciences)

شهریار صانع | shahryar sane
department of anesthesiology, fellowship of neuroanesthesia, assistant professor of urmia university of medical sciences, urmia, iran
urmia university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ارومیه (Urmia university of medical sciences)

نسیم عالی دایی | nasim alidaei
urmia university of medical sciences, urmia, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ارومیه (Urmia university of medical sciences)

شقایق رحیمی راد | shaghaiegh rahimi rad
tabriz university of medical sciences, tabriz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)


نشانی اینترنتی http://umj.umsu.ac.ir/browse.php?a_code=A-10-2664-3&slc_lang=en&sid=fa
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زبان مقاله منتشر شده fa
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نوع مقاله منتشر شده پژوهشی(توصیفی- تحلیلی)
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