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Iranian Journal of Kidney Diseases، جلد ۱۰، شماره ۴، صفحات ۲۰۵-۰
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عنوان انگلیسی Association Between 25-Hydroxyvitamin D Level and Inflammatory and Nutritional Factors in Hemodialysis and Peritoneal dialysis Patients in Qom, Iran
چکیده انگلیسی مقاله Introduction. This study aimed to evaluate the prevalence of vitamin D inadequacy in patients receiving maintenance hemodialysis and peritoneal dialysis (PD) and its association with inflammatory and nutritional factors. Materials and Methods. A total of 176 hemodialysis and 32 PD patients participated in the study. Serum levels of 25-hydroxyvitamin D, albumin, parathyroid hormone, calcium, phosphorus, high-sensitivity C-reactive protein (HSCRP), and neutrophil-lymphocyte ratio (NLR) were measured. Data on body mass index were also collected. Stepwise multiple logistic regression analysis was used to identify predictors for 25-hydroxyvitamin D deficiency and its relationship with the nutritional and inflammatory factors. Results. No significant association was found between 25-hydroxyvitamin D and age, body mass index, serum calcium, serum phosphorus, parathyroid hormone, serum albumin, dialysis quality, and duration of dialysis; while NLR and HSCRP were significantly associated with 25-hydroxyvitamin D in the hemodialysis patients only ( P < .001 and P = .001, respectively). A positive correlation was found between NLR and HSCRP in both hemodialysis and PD patients. (r = 0.817; P < .001). This association was confirmed between an NLR greater than 3 and an HSCRP level greater than 3. Conclusions. Vitamin D deficiency was highly prevalent in our dialysis patients, and inadequate level of vitamin D was associated with inflammatory factors such as HSCRP and NLR in both hemodialysis and PD patients. An easy and inexpensive test of an NLR greater than 3 could be used as a measure of inflammation instead of HSCRP in both PD and hemodialysis patients.
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نویسندگان مقاله الهام میر chi | elham mir chi


حسین ثقفی | hosein saghafi


محمد قره beg lou | mohamad ghareh beg lou


محمد آقا علی | mohamad agha ali


زهرا rezaeiann | zahra rezaeiann


معصومه قوی ahd | masoumeh ghavi ahd


نشانی اینترنتی http://www.ijkd.org/index.php/ijkd/article/view/2480
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