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Iranian Journal of Kidney Diseases، جلد ۷، شماره ۳، صفحات ۱۸۷-۰
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عنوان انگلیسی Seroepidemiology of Human T-cell Lymphotropic Virus 1 Infection in Hemodialysis Patients: Should We be Concerned About it?
چکیده انگلیسی مقاله Human T-cell lymphotropic virus 1 (HTLV1) is a lymphotropic virus which can be transmitted through unprotected sexual activity, breast feeding, and blood transfusion. Although most of HTLV1-infected individuals remain asymptomatic carriers, 1% to 5% and 3% to 5% develop adult T-cell leukemia and HTLV1-associated myelopathy/tropical spastic paraparesis, respectively. The aim of this study was to determine the prevalence of HTLV1 infection in hemodialysis patients in Sari and Ghaemshahr. This cross-sectional study was conducted on160 patients using random samples selection, and included 80 men and 80 women (mean age, 59.1 ± 14.7 years). All the samples were screened for HTLV1 antibody b y enzyme-linked immunosorbent assay and positive samples were confirmed by Western blot assay. Only 1 patient had a positive anti-HTLV1 enzyme - linked immunosorbent assay test, which was confirmed by Western blot. The overall prevalence of HTLV1 seropositivity was 0.6%. The patient was a 21-year-old woman with a history of multiple blood transfusions. She had a history of unsuccessful kidney transplantation and had been on hemodialysis before transplant, too. This study suggests that HTLV1 infection may not be prevalent in high-risk patients in Mazandaran province, and there is no need for HTLV1 screening of blood samples.
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نویسندگان مقاله جواد غفاری | javad ghaffari


محبوبه ابراهیمی | mahbobeh ebrahimi


عطیه مخلوق | atieh makhlough


حمید محمدجعفری | hamid mohammadjafari


زینب نظری | zeinab nazari


نشانی اینترنتی http://www.ijkd.org/index.php/ijkd/article/view/832
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده SPECIAL REPORT | Dialysis
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