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JCR 2016
جستجوی مقالات
چهارشنبه 26 آذر 1404
Iranian Journal of Kidney Diseases
، جلد ۵، شماره ۴، صفحات ۲۵۵-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Measurement of Serum Levels of Mannose-binding Lectin in Hemodialysis Patients: A Comparison With Healthy Individuals
چکیده انگلیسی مقاله
Introduction. Mannose-binding lectin (MBL) is a part of the innate immune system. Many studies showed an association of low serum MBL levels with decreased host defense against various infectious agents. Considering paradoxical reports about the serum level of MBL in hemodialysis patients, this study aimed to measure and compare serum MBL levels in hemodialysis patients and healthy individuals. Materials and Methods. In a cross-sectional study, 70 hemodialysis patients and 70 volunteers with normal routine laboratory tests and physical examination were assessed for serum MBL level (measured by an enzyme-linked immunosorbent assay). In addition, serum C-reactive protein levels in hemodialysis patients were measured to rule out correlation of increased serum MBL level with inflammation. Results. In hemodialysis patients, 32 (45.7%) were men and 38 (54.3%) were women. In the control group, 34 (48.6%) were men and 36 (51.4%) were women (P = .87). The mean age showed no significant difference in hemodialysis (44.5 ± 13.5 year) and control (46.4 ± 12.4 years) groups. Serum level of MBL was significantly higher in hemodialysis patients (2.12 ± 1.49 ?g/mL) than that in the controls (1.49 ± 2.12 ?g/mL; P Conclusions. Serum MBL level in hemodialysis patients was significantly higher than that in the control group of healthy individuals. This may have some implications in management of patients and prediction of kidney allograft survival.
کلیدواژههای انگلیسی مقاله
نویسندگان مقاله
رقیه اکبری | roghayeh akbari
مسعود میراسکندری | masoud mireskandari
رضا علیزاده نوایی | reza alizadeh navaei
احد قدس | ahad ghods
نشانی اینترنتی
http://www.ijkd.org/index.php/ijkd/article/view/237
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زبان مقاله منتشر شده
en
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نوع مقاله منتشر شده
ORIGINAL | Dialysis
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