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Iranian Journal of Kidney Diseases، جلد ۴، شماره ۴، صفحات ۳۲۷-۰
عنوان فارسی
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عنوان انگلیسی Effect of High-flux Versus Low-flux Dialysis Membranes on Parathyroid Hormone
چکیده انگلیسی مقاله Introduction. Hyperparathyroidism is a common finding in patients with renal insufficiency and parathyroid hormone (PTH) is considered a uremic toxin responsible for many of the abnormalities of the uremic state and bone disease. The aim of this study was to investigate the influence of permeability of low-flux versus high-flux dialysis membranes on intact PTH during hemodialysis in children. Materials and Methods. Forty-four children aged between 4 and 13 years old on regular hemodialysis were enrolled in a prospective study. Low-flux polysulfone membranes were used for at least 6 months and then the patients were switched to use high-flux polysulfone membranes for 3 months. Serum electrolytes and intact PTH before and after dialysis were compared before and after changes in dialysis membrane. Results. At the end of the 3-month use of high-flux filters, predialysis intact PTH level (49.40 ± 19.64 ng/dL) showed a highly significant decline (P Conclusions. In children, high-flux dialysis membranes are more efficient in removal of intact PTH, one of the middle-sized uremic toxins, than low-flux membranes.
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نویسندگان مقاله سامویل helmy makar | samuel helmy makar


happy kayser sawires | happy kayser sawires


tarek محمد فرید | tarek mohamed farid


waleed محمد علی | waleed mohamed ali


مونا schaalan | mona schaalan


نشانی اینترنتی http://www.ijkd.org/index.php/ijkd/article/view/306
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده ORIGINAL | Dialysis
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