این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Kidney Diseases، جلد ۴، شماره ۱، صفحات ۶۶-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Gingival Enlargement and Its Risk Factors in Kidney Transplant Patients Receiving Cyclosporine A
چکیده انگلیسی مقاله Introduction. Gingival enlargement is one of the most cumbersome complications of cyclosporine A. It affects patient’s life style by impairing the appearance and function of masticatory tract. This study was conducted on a sample of Iranian kidney transplant recipients to determine the frequency and risk factors of cyclosporine-induced gingival enlargement. Materials and Methods. A total of 200 kidney transplant recipients (mean age, 39.7 ± 13.2 years) were enrolled in this study. All of the participants were receiving cyclosporine for at least 12 months prior to the study. Factors including age, gender, cyclosporine dose, serum concentration of cyclosporine, duration of immunosuppressive administration, plaque, and gingival indexes were evaluated. Results. Seventy kidney transplant recipients (35%) showed various degrees of gingival enlargement. Serum cyclosporine concentration and the intensity of gingival enlargement (McGraw index) had a significant correlation (r = 0.35, P < .001). Multiple regression analysis revealed an independent association between gingival enlargement and either serum concentrations of cyclosporine and plaque index (P < .05). The other variables failed to show a significant relationship with gingival enlargement. Conclusions. The prevalence of cyclosporine-induced gingival enlargement in our patients seems to be almost greater than the prevalence reported in previous studies. There was a significant relationship between cyclosporine immunosuppressive treatment and gingival overgrowth in Iranian kidney transplant recipients.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله علی غفاری | ali ghafari


رضا پورعباس | reza poorabbas


جیمز انویه تکیه | james anvieh takieh


نریمان سپهروند | nariman sepehrvand


catauoun کارگر | catauoun kargar


ساناز حاتمی | sanaz hatami


نشانی اینترنتی http://www.ijkd.org/index.php/ijkd/article/view/195
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده ORIGINAL | Transplantation
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات