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Iranian Journal of Kidney Diseases، جلد ۱، شماره ۲، صفحات ۷۸-۰
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عنوان انگلیسی Influence of Dialysis Duration, Peritoneal Transport Parameters, and Gender on Effluent CA125 Concentration in Patients on Peritoneal Dialysis
چکیده انگلیسی مقاله Introduction. Peritoneal effluent cancer antigen 125 (CA125) concentration is a marker of mesothelial cell mass in patients on continuous ambulatory peritoneal dialysis (CAPD). Accordingly, we aimed to observe the effects of CAPD duration, sex, and peritoneal membrane efficacy on CA125 levels in peritoneal effluent. Materials and Methods. In 30 patients who were on CAPD for 6 months, concentrations of CA125 were determined in the 4-hour effluent peritoneal dialysate at the 6th and 12th month of CAPD initiation. The laboratory results were assessed in relation to the patients’ sex and peritoneal membrane efficacy which was measured by the peritoneal equilibration test, weekly creatinine clearance, and the Kt/V. Results. The patients were 16 men and 14 women with a mean age of 34.3 years (range, 17 to 56 years). With increasing the duration of CAPD, dialysate CA125 levels decreased significantly (P Conclusions. We found that peritoneal effluent CA125 level decreases in both men and women with increasing of CAPD duration, without any association with peritoneal transport parameters. Of interest, there was a gender difference in the CA125 levels in our series.
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نویسندگان مقاله محمد جواد مجاهدی | mohammad javad mojahedi


مریم حامی | maryam hami


محمد تقی شاکری | mohammad taghi shakeri


رضا حکمت | reza hekmat


نشانی اینترنتی http://www.ijkd.org/index.php/ijkd/article/view/49
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نوع مقاله منتشر شده ORIGINAL | Dialysis
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