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Journal of Medical Microbiology and Infectious Diseases، جلد ۵، شماره ۱، صفحات ۰-۰
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عنوان انگلیسی Trichosomoides crassicauda Infection in Laboratory Rats with Histopathological Description in the Bladder Tissue
چکیده انگلیسی مقاله Introduction: Some postgraduate students reported the presence of a nematode infection, presumably, Trichosomoides crassicauda in the urinary bladder of rats (Rattus norvegicus) from the animal house of Tehran University of Medical Sciences (TUMS). We prompted to explore the prevalence of this infection among the rats of animal houses belonging to medical and veterinary research centers in Tehran. We also described the histopathological changes in the bladder tissue of the infected rats. Methods: We collected 214 adult rats (R. norvegicus) from four animal houses including TUMS in Tehran. The urine of 112 animals was collected during 24 h and inspected microscopically for helminths eggs. Then, the rats were euthanized, sacrificed and dissected; their bladders were removed and examined under a stereomicroscope for the presence of worms and histopathological changes. Results: Out of 112 urine samples checked, 16 contained T. crassicauda eggs. Out of 214 rats, 114 showed infection urinary bladder with the nematode T. crassicauda. The histopathological changes in the urinary bladder included hyperemia, edema, hyperplasia, and metaplasia. In the transitional epithelium, the features of gravid female nematodes, with an egg-filled uterus were visible. Conclusion: Trichosomoides crassicauda is a prevalent infection in laboratory rats of research centers in Tehran and its identification cannot be made merely based on urine examination of the rats.
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نویسندگان مقاله فایزه نجفی | faezeh najafi
department of parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مایده تقوی قادیکلایی | maede taghavi ghadikolai
department of biology, faculty of sciences, university of mohaghegh ardabili, ardabil, iran


سعید رضا نداف | saied reza naddaf
department of parasitology, research center for emerging and reemerging diseases pasteur institute of iran, tehran, iran

سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

حمید حسن پور | hamid hasanpour
department of parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

ایرج موبدی | iraj mobedi
department of parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

غلامرضا مولوی | gholamreza mowlavi
department of parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://jommid.pasteur.ac.ir/browse.php?a_code=A-10-154-1&slc_lang=en&sid=en
فایل مقاله دریافت فایل مقاله
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Animal Models
نوع مقاله منتشر شده Original article
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