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Iranian Journal of Microbiology، جلد ۹، شماره ۶، صفحات ۳۴۸-۳۵۵
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Antagonistic activities of some probiotic lactobacilli culture supernatant on Serratia marcescens swarming motility and antibiotic resistance
چکیده انگلیسی مقاله Background and Objectives: Serratia marcescens , a potentially pathogenic bacterium, benefits from its swarming motility and resistance to antibiotic as two important virulence factors. Inappropriate use of antibiotics often results in drug resistance phenomenon in bacterial population. Use of probiotic bacteria has been recommended as partial replacement. In this study, we investigated the effects of some lactobacilli culture supernatant on swarming, motility and antibiotic resistance of S. marcescens . Materials and Methods: Antimicrobial activity of lactobacilli supernatant and susceptibility testing carried out on S. marcescens isolates. Pretreatment effect of lactobacilli culture supernatant on antibiotic - resistance pattern in S. marcescens was determined by comparison of the MIC of bacteria before and after the treatment. Results: Our results showed that pretreatment with L. acidophilus ATCC 4356 supernatant can affect the resistance of Serratia strains against ceftriaxone, but it had no effect on the resistance to other antibiotics. Furthermore, culture supernatant of lactobacilli with concentrations greater than 2%, had an effect on the swarming ability of S. marcescens ATCC 13880 and inhibited it. Conclusion: Probiotic bacteria and their metabolites have the ability to inhibit virulence factors such as antibiotic resistance and swarming motility and can be used as alternatives to antibiotics.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله رویا واحدی شاهاندشتی | roya vahedi shahandashti
department of microbiology, faculty of biological sciences, alzahra university, tehran, iran

سازمان اصلی تایید شده: دانشگاه الزهرا (Alzahra university)

روحا کسری کرمانشاهی | rouha kasra kermanshahi
department of microbiology, faculty of biological sciences, alzahra university, tehran, iran

سازمان اصلی تایید شده: دانشگاه الزهرا (Alzahra university)

ملیحه shokouhfard | maliheh shokouhfard
department of biotechnology, faculty of biological sciences, alzahra university, tehran, iran

سازمان اصلی تایید شده: دانشگاه الزهرا (Alzahra university)

پریناز قدم | parinaz ghadam
department of microbiology, school of medicine, tehran university of medical sciences, tehran, iran; thoracis research center, imam khomeini hospital, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محمد مهدی فیض آبادی | mohammad mehdi feizabadi
department of medical genetics, iran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

شهرام تیموریان | shahram teimourian


نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/1360
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/91/article-91-565929.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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