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Iranian Journal of Public Health، جلد ۴۷، شماره ۲، صفحات ۲۶۴-۲۷۲
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Virulence Determinants and Antimicrobial Resistance Patterns of Vancomycin-resistant Enterococcus faecium Isolated from Different Sources in Southwest Iran
چکیده انگلیسی مقاله Abstract Background: This study aimed to investigate the incidence of antibiotic-resistance and virulence genes in vancomycin-resistant Enterococcus faecium isolated from different sources in southwest Iran from Mar to Sep 2015. Methods: Overall, 120 E. faecium isolates (80 VRE and 40 vancomycin-susceptible enterococci [VSE] isolates) were obtained from four hospitals. The resistance of the VRE isolates was determined by disk diffusion method. Multiplex PCR was performed to detect the virulence genes carried by the E. faecium isolates, namely, enterococcal surface protein ( esp ), hyaluronidase ( hyl ), and collagen-binding adhesin ( acm ). Results: All the VRE isolates exhibited multidrug resistance, with the rates of resistance to ampicillin, erythromycin, and ciprofloxacin reaching high levels. The isolates were least resistant to chloramphenicol and nitrofurantoin, but all of them were susceptible to linezolid. 46.6%, 20.8%, and 86.6% of the E. faecium isolates carried the esp , hyl , and acm genes, respectively. Conclusion: There is a significant difference between the prevalence of esp and hyl genes in the VRE and VSE isolates . In the VRE isolates, the high prevalence of multidrug resistance were found and the difference in the prevalence of esp among various sources was significant. The findings reflected a relationship between the prevalence of esp and hyl and resistance to certain antibiotics.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله مانیا ارشدی | maniya arshadi
dept. of epidemiology and biostatistics, school of public health, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محمود محمودی | mahmood mahmoudi
dept. of microbiology, school of medicine, ahwaz jundishapur university of medical sciences, ahwaz, iran


مولود سادات مطهر | moloud sadat motahar
dept. of pathobiology, school of public health, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

صابر سلطانی | saber soltani
dept. of pathobiology, school of public health, tehran university of medical sciences, tehran, iran urology research center, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محمدرضا پورمند | mohammad reza pourmand


نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/12411
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/86/article-86-566972.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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