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The Archives of Bone and Joint Surgery، جلد ۶، شماره ۲، صفحات ۰-۰
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عنوان انگلیسی Combination of bone marrow derived cells transplantation and high tibial osteotomy in early osteoarthritis of knee: A preliminary study
چکیده انگلیسی مقاله Purpose: high tibial osteotomy (HTO) is a recommended treatment for medial compartment knee osteoarthritis. Newer cartilage regenerative procedures may add benefits to the result of HTO. In this prospective study we investigate safety and also results of HTO associated with bone marrow derived cells (BMDC) transplantation in relatively young and middle aged active individuals with early osteoarthritis of the knee and our hypothesis is combination of these procedures is safe and leads to better outcome. Methods: 24 patients (with mean age of 47.9 years) with varus knee and symptomatic medial compartment osteoarthritis were treated with medial opening-wedge high tibial osteotomy in conjunction with transplantation of bone marrow derived cells into the chondral lesions. Clinical outcome was assessed by IKDC score, KOOS score, VAS and Tegner scores and radiographic study was performed preoperatively and at follow-ups. Results: there were no major complications during operation and postoperative follow-ups.all the clinical scores significantly were improved for the IKDC score (from 32.7 +/-15 to 64+/- 21), KOOS score (from30 +/- 11 to 68 +/- 19), VAS (from7.5 to 3), and Tegner score (from 1.2 to 2.1). Conclusions: HTO in conjunction with BMDC transplantation is a safe and feasible treatment for early medial compartment osteoarthritis in varus knees and associated with good results in short term follow up.
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نویسندگان مقاله مارکو cavallo | marco cavallo
department of orthopaedics and traumatology, rizzoli orthopaedic institute, via pupilli, bologna, italy


سید هادی سید حسینیان | sayyed hadi sayyed hosseinian
orthopedic research center, shahid kamyab hospital, mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

alessandro parma | alessandro parma
department of orthopaedics and traumatology, rizzoli orthopaedic institute, via pupilli, bologna, italy


روبرتو buda | roberto buda
department of orthopaedics and traumatology, rizzoli orthopaedic institute, via pupilli, bologna, italy


massimiliano mosca | massimiliano mosca
department of orthopaedics and traumatology, rizzoli orthopaedic institute, via pupilli, bologna, italy


sandro giannini | sandro giannini
department of orthopaedics and traumatology, rizzoli orthopaedic institute, via pupilli, bologna, italy
نشانی اینترنتی http://abjs.mums.ac.ir/article_10406.html
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/328/article-328-574376.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده RESEARCH PAPER
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