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Acta Medica Iranica، جلد ۵۶، شماره ۳، صفحات ۱۷۶-۱۸۰
عنوان فارسی
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عنوان انگلیسی Growth and development status in the first two years of uninfected children born from HIV positive mothers
چکیده انگلیسی مقاله Recently prevention of HIV transmission from mother to child by antiretroviral regimens has resulted in growing the numbers of HIV exposed but uninfected children (HIV-EU). The aim of present study was evaluation of growth and neurodevelopment status among less than 2-year-old HIV exposed uninfected children. A cohort study was carried out at Vali-e-Asr Hospital (Tehran-Iran). Thirty-nine HIV-EU neonates were recruited (2014 to 2016). Neonates and infants with concern to growth and neurodevelopment status were evaluated at 6, 12, 18, and 24 months by an expert physician. Neurodevelopment assessment was based on WHO Milestones Chart and Age and Stage Questionnaire. Of all children, 22 were male, and 17 were female. Regarding growth indices, although mean birth weight in half of the neonates was lower than normal population; no postnatal descending trend was observed in their growth chart. No significant differences were found between two groups' height and head circumference. Among the neurodevelopmental parameters measured, in 6 th months of life, 2 cases had abnormality in the gross motor while at 12 months, 6 cases had delay in language, social problem, and motor disorders. At 18 and 24 months, 7 infants showed developmental problems of which 71.4% of their mothers were younger than others (age< 25 years, P =0.009). Prevalence of neurodevelopmental disorders including delay in language, motor, and social domains was common among HIV-EU children. As several environmental factors may involve the etiology of neurodevelopmental disorders, nearly-full postnatal control and prevention seem necessary.
کلیدواژه‌های انگلیسی مقاله HIV seronegativity,Infant,Growth,Development
نویسندگان مقاله | Hosein Dalili
Department of Neonatology, Breast Feeding Research Center, Family Health Institute, Tehran University of Medical Sciences, Tehran, Iran.


| Yasamin Mohamadzadeh
Department of Community Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.


| Farnoush Davoudi
Department of Neonatology Maternal, Fetal and Neonatal Research Center, Family Health Institute, Tehran University of Medical Sciences, Tehran, Iran.


| Zahra Farahani
Department of Infectious Diseases, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.


| Mehrnaz Rassolinejad
Department of Neonatology Maternal, Fetal and Neonatal Research Center, Family Health Institute, Tehran University of Medical Sciences, Tehran, Iran.


| Mamak Shariat
Department of Neurology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| Amirali Ghahramani


نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/6585
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/56/article-56-575571.pdf
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