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Journal of Dental Materials and Techniques، جلد ۷، شماره ۲، صفحات ۸۳-۸۸
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عنوان انگلیسی Hepatitis B Virus Infection and Oral Lichen Planus: A Report from Northeast of Iran
چکیده انگلیسی مقاله Introduction: Lichen planus is a chronic inflammatory disease in oral mucosa and skin. Recently, reports have demonstrated a possible relationship between lichen planus and liver diseases. During the past decade, there has been a hypothesis regarding viral etiological agents that have been found to be in association with hepatotrophic viruses known as Hepatitis B and C with LP. This research was studied in Mashhad, northeast of Iran, to find a relationship between OLP and HBV infection. Methods: Age and gender of 134 patients (with OLP) and 134 controls (without OLP) were not matched and their serum samples were respectively screened for HBsAg by ELISA (third generation) and polymerase chain reaction (PCR) for HBV-DNA. Results: Tests were positive (for both HBsAg and HBV-DNA) for 9 patients (6.71%) with OLP and 2 healthy individuals (1.49%) infected with HBV (P=0.03). Conclusion: There was a relationship between HBV and OLP in our population. Based on our findings, it is recommended that viral serology for Hepatitis B and OLP patients be conducted as a routine screening process.    
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نویسندگان مقاله | Mohammad Amin Khajavi
Oral & Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran


| Zahra Meshkat
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran


| Alireza Pasdar
Department of Modern Sciences and Technologies, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


| Ala Ghazi
Oral & Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran


| Sina Gerayli
Division of Applied Medicine, Medical School, University of Aberdeen, Foresterhill, Aberdeen, UK


| Elham Banihashemi
Department of Biology, Western University, London, Ontario, N6A 5B7, Canada


| Pegah Mosannen Mozafari
1Oral & Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
نشانی اینترنتی http://jdmt.mums.ac.ir/article_10508.html
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/278/article-278-578259.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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