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Journal of Craniomaxillofacial Research، جلد ۵، شماره ۱، صفحات ۴۶۱-۴۶۷
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عنوان انگلیسی Human dental pulp stem cells differentiation: A review
چکیده انگلیسی مقاله The advent of regenerative medicine has brought us the opportunity to regenerate, modify and restore human organs function. Stem cells, a key resource in regenerative medicine, are defined as clonogenic, self-renewing, progenitor cells that can generate into one or more specialized cell types. Human dental pulp stem cells (HDPSCs) are ectodermal-derived stem cells, originating from migrating neural crest cells and are capable of providing enough cells for potential cell-based therapies. During last decade, HDPSCs have received extensive attention in the field of tissue engineering and regenerative medicine due to their accessibility and ability to differentiate in several cell phenotypes. In this review, we have described the potential of HDPSCs to differentiate into odontoblasts, osteoblasts, hepatocytes, neuroblasts and angioblasts in response to different bioactive factors. Therefore, the culture and selective differentiation of HDPSCs should provide further understanding of dental pulp progenitors and their potential use for new therapeutic approaches in regenerative medicine. Keywords : Human dental pulp stem cells, HDPSCs, Differentiation, Bioactive factors, Inductive factors.
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نویسندگان مقاله | Elham Mohammadi Golrang
Department of Endodontics, Faculty of dentistry, Tehran University of Medical Sciences, International Campus, Tehran, Iran.


| Fatemeh Dibaji
Craniomaxillofacial Research Center, Oral and Maxillofacial Surgery Department, Faculty of dentistry, Tehran University of Medical Sciences, Tehran, Iran.


| Naghmeh Bahrami
Department of Kinesiology and Physical Education, McGill University, Montreal, Quebec, Canada.


| Atena Mohammadi Golrang


نشانی اینترنتی http://jcr.tums.ac.ir/index.php/jcr/article/view/206
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/364/article-364-582446.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Review Article(s)
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