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Iranian Journal of Medical Sciences، جلد ۴۳، شماره ۳، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Frequency of Smear-Negative Tuberculosis in Northwest Iran
چکیده انگلیسی مقاله Background: Microscopic smear examination is the most common test in tuberculosis (TB) detection. It is, however, not strong enough to identify TB in the majority of afflicted individuals; thus, a significant number of TB patients are smear negative and capable of transmitting the infection. The aim of this study was to evaluate the rate of smear-negative TB in northwest Iran. Methods: In this cross-sectional study, 329 TB-confirmed patients were evaluated through culture up to March 1, 2015, in northwest Iran. The demographic and clinical features of the smear-negative and smear-positive TB patients were compared. The χ2 test was used to compare the frequency of the variables. All the statistical analyses were conducted using SPSS, version 16 (Chicago, IL, USA). Results: Seventy-five cases were smear negative and 254 were smear positive. Smokers, asthmatics, and extra-pulmonary TB patients were primarily among the smear-negative cases. The rate of mortality was also relatively higher among the smear-negative TB patients. Conclusion: Totally, 22.8% of the TB cases in northwest Iran were smear negative, with a relatively higher rate of mortality than those with positive smears. A delay in these patients’ return to TB diagnosis and treatment centers increases the chance of transmission to others. This is a very sensitive issue in centers where there is no equipment for TB cultivation. Thus, it is essential to equip centers without TB cultivation facilities and to use appropriate diagnostic techniques in centers with those facilities to help rapidly detect smear-negative cases.
کلیدواژه‌های انگلیسی مقاله Culture, Diagnosis, Epidemiology, Smear, Tuberculosis
نویسندگان مقاله | Mahya Pourostadi
Department of Laboratory Science, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran; and Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran;


| Jalil Rashedi
Department of Laboratory Science, Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran; and Department of Medical Parasitology, School of Medical Sciences, Tarbiat Modarres University, Tehran, Iran


| Behroz Mahdavi Poor
Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran


| Hossein Samadi Kafil
Adjunct Lecturer, Faculty of Health and Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran


| Maral Hariri-Akbari
Biotechnology Research Center and Faculty of Paramedicine, Tabriz University of Medical Sciences, Tabriz, Iran


| Mohammad Asgharzadeh


نشانی اینترنتی http://ijms.sums.ac.ir/index.php/IJMS/article/view/3396
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/147/article-147-590193.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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