این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Physiology and Pharmacology، جلد ۱۵، شماره ۲، صفحات ۲۴۱-۲۴۸
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Acute effect of burn trauma to small skin areas on myocardial ischemia reperfusion
چکیده انگلیسی مقاله Introduction: It has been reported that traumas such as transverse abdominal incision before myocardial ischemia result in a significantly decreased infarct size. This phenomenon is named remote preconditioning of trauma. Since small skin burn is one of most common traumas, the effect of this injury on ischemia-induced arrhythmias and infarct size was investigated in a rat model of ischemia-reperfusion injury. Methods: Twenty-four male Wistar rats were randomly assigned to 3 groups. In burn and sham groups, less than 1% of total body surface area of the dorsal skin was exposed to 100 ˚C and 37 ˚C water, respectively. In ischemic preconditioning group, rats were exposed to one cycle of ischemia (5 min) and reperfusion (10 min). Ischemiareperfusion injury was induced with occlusion and release of left coronary artery for 30 and 120 min, respectively. Infarct size was measured using triphenyl tetrazolium chloride staining and arrhythmias were assessed in accordance with Lambeth conventions. Results: Infarct size was significantly reduced in ischemic preconditioning group compared with the sham group (27 ± 2% vs. 50 ± 5% P < 0.01). Infarct size in the burn group was not significantly reduced. Irreversible ventricular fibrillation was 50% of all ventricular fibrillation in the burn group, while it was 25% in the sham group, however, this difference was not significant. Conclusion: Acute minor coetaneous burn has neither protective nor harmful for the rat myocardial ischemiareperfusion injury.
کلیدواژه‌های انگلیسی مقاله Burn, Ischemia, Infarct size, Arrhythmia
نویسندگان مقاله شهناز shekarforush | shahnaz shekarforush
trauma research center, bagiyatallah university of medical science, tehran, iran.


علی نوروززاده | ali noroozzadeh
physiology and biophysics department, school of medicine, bagiyatallah university of medical science, tehran, iran


فاطمه صفری | fatemeh safari
department of physiology, shahid sadoughi university of medical sciences, yazd, iran


لیلا golmanesh | leila golmanesh
research center for molecular biology, bagyatallah university of medical science, tehran, iran


علی خوش باطن | ali khoshbaten
trauma research center, bagiyatallah university of medical science, tehran, iran.
نشانی اینترنتی http://www.phypha.ir/ppj/browse.php?a_code=A-10-494-2&slc_lang=en&sid=en
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Cardivascular system
نوع مقاله منتشر شده Original Research
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات