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Nanomedicine Journal، جلد ۵، شماره ۳، صفحات ۱۲۷-۱۳۷
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عنوان انگلیسی A study on the possibility of drug delivery approach through ultrasonic sensitive nanocarriers
چکیده انگلیسی مقاله Physical drug delivery through smart nanocarrier and external stimulus could lead to significant improvements of drug potency as well as noticeable decrease in unwanted side effects. Currently, many external energy sources such as light, magnetic fields, ultrasound, ...,  are under investigation as external stimulus for physical drug delivery. The purpose of this paper is to review most recent developments of triggered release of drugs and biomolecules under external ultrasound exposure. A special attention has also been paid to the metal nanostructures for ultrasound mediated drug delivery and also, other nanostructures were also considered. We briefly introduced ultrasound regulation and safety consideration. Further it is concluded that the use of nanostructures for delivery of active biomolecules in combination with ultrasound as a stimulus to trigger drug release from the nanocarriers and increased drug penetration has gained much attention for effective drug delivery and overcoming difficulties of multi-drug resistance of cancer.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Ali Akbar Karimi Zarchi
Nanobiotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran


| Seyed Mohammad Amini
Radiation Biology Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran|Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran


| Zohreh Jomehfarsangi
Department of Medical Nanotechnology, School of Advanced Technologies in Medicine (SATiM), Tehran University of Medical Sciences (TUMS), Tehran, Iran


| Elham Mohammadi
Radiation Biology Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran|Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran


| Zahra Moosavi
Department of Nursing, School of Nursing and Midwifery, Lorestan University of Medical Sciences, Boroujerd, Iran


| Parisa Ghadiri Harrati
Department of Physiotherapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
نشانی اینترنتی http://nmj.mums.ac.ir/article_11159.html
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/295/article-295-689467.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Review Paper
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