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گوارش، جلد ۲۱، شماره ۱، صفحات ۶۴-۰
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عنوان انگلیسی Association between Vitamin D Deficiency and the Severity of Chronic Liver Disease and Liver Cirrhosis: Systematic Literature Review
چکیده انگلیسی مقاله Background Vitamin D deficiency is believed to cause variety of abnormalities such as liver stiffness and fibrosis. It is also shown that vitamin D deficiency may result in chronic liver disease or liver cirrhosis. In this study, we aimed to systematically review the literature wherein the relationship between vitamin D deficiency and the severity of chronic liver disease or liver cirrhosis had been investigated. Materials and Methods PubMed, Scopus, and Google scholar were searched using the following search method (((vitamin D deficiency OR vitamin D insufficiency OR insufficient vitamin D)) AND (chronic liver disease OR chronic hepatitis OR cirrhosis OR liver cirrhosis)) AND (severity OR intensity) to evaluate the role of vitamin D deficiency or vitamin D inadequacy in the occurrence and severity of chronic liver disease. Articles were collected and the data were extracted. Results Totally, 641 articles were found through searching the databases and reference list scanning. Of the collected documents, only 19 articles with 4895 studied patients were included and analyzed. The results of this study showed that almost 80% of patients with chronic liver disease had severe vitamin D deficiency. Conclusion Vitamin D deficiency is associated with the occurrence of chronic liver disease. The severity of liver cirrhosis is also associated with the level of 25(OH)D in progressive liver disease.
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نویسندگان مقاله حسین علی عباسی | hosein ali abbasi


عباس esmaeeilzadeh | abbas esmaeeilzadeh


هومن مسنن مسنن مظفری | homan mosanan mosannen mozaffari


علی بهاری | ali bahari


کامبیز اخوان رضایت | kambiz akhavan rezayat


امید قناعی | omid ghanaei


آزیتا گنجی | azita ganji


علی مختاری فر | ali mokhtarifar


لادن گشایشی | ladan goshayeshi


نشانی اینترنتی http://www.govaresh.org/index.php/dd/article/view/1473
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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