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عنوان انگلیسی Diagnostic Value of Serology Versus Pathology in Diagnosis of Helicobacter Pylori Infection
چکیده انگلیسی مقاله Introduction: Helicobacter pylori infection is likely acquired was in childhood. Helicobacter pylori is recognized as a cause of gastritis and peptic ulcer. Our objective to investigate some noninvasive tests, particularly serum H pylori IgG, for the diagnosis of H pylori infection in comparison with the gold-standard invasive test, esophagogastroduodenoscopy with biopsy (histology and rapid urease test). Materials and Methods: We studied 100 patients (age range: 6-18 years) who underwent esophagogastroduodenoscopy with biopsy (histologic examination) for a suspicious upper gastrointestinal disease, in all of them serum Hpylori immunoglobulin G was measured and result of this were compared with those of the gold standard esopahgogastrodudenoscopy with biopsy. Results: Of 100 patients (60 males, 40 females), 91% had history of gastrointestinal disease and 29% had positive family history for gastrointestinal disease. gastritis, ulcer and erosion were found respectively in 94%, 31%, 34% of patients. Rapid urease test, serology and histology were positive respectively in 57%, 23%, and 29% of patients. In comparison with histology sensitivity of serology was 45% and it's specificity was 71%. Conclusion: serum Hpylori IgG test has a low sensitivity and specificity in children in comparison with the gold standard invasive test.
کلیدواژه‌های انگلیسی مقاله Culture,Helicobacter pylori,Pathology,Serology.

نویسندگان مقاله seyedmohammadmehdi میر ناصری | seyedmohammadmehdi mir nasseri


فاطمه یوردخانی | fatemeh yourdkhani


بهار اله وردی | bahar allahverdi


فریده سیاوشی | farideh siavoshi


غلامرضا خاتمی | golamreza khatami



نشانی اینترنتی http://www.govaresh.org/index.php/dd/article/view/599
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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