این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
گوارش، جلد ۱۳، شماره ۴، صفحات ۲۲۳-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Effects of using Mitomycin-C in Treatment of Benign Esophageal Strictures
چکیده انگلیسی مقاله Background: Using bouginage or balloon dilatation is the standard treatment for benign esophageal strictures. AÙŽbout two-thirds need repeated dilatations. For preventing recurrent strictures, many medications such as mitomycin-C have been used. Mitomycin-C is a special antibiotic with anti-neoplastic characteristics, which inhibits fibroblast proliferation, reduces collagen production and decreases scar formation. Materials and Methods: In this study, 12 patients with benign esophageal stricture during Azar 1386 to Bahman 1387 in Imam Khomeini Endoscopy Department were included.ٍ Esophageal endoscopy was done and mitomycin-C was applied on the place of stricture using a cotton ball. Then, response to treatment was categorized in three groups of complete response, partial response and non-response to treatment. Results: Average number of using mitomycin-C was 4 ± 3 times. Mean interval between endoscopies before using mitomycin-C was 3.5 ± 1 weeks and after using this agent was 8.5 ± 4.3 weeks. There were 4 cases of complete response, 5 cases of partial response and 3 patients of non-response. Conclusion: Conservative treatments in management of benign esophageal strictures are preferred to more invasive treatments. However, it seems using a topical solution of mitomycin-C carries better responses and reduces the rate of recurrent dilatations.
کلیدواژه‌های انگلیسی مقاله Esophageal stricture,Dilatation,Mitomycin-C.
نویسندگان مقاله علیرضا مومنی | alireza momeni


محمد مجلسی | mohmmad majlesi


ناصر ابراهیمی دریانی | naser ebrahimi daryani


محمدرضا کرامتی | mohammadreza keramati


پیمان حبیب اللهی | peyman habibollahi


نشانی اینترنتی http://www.govaresh.org/index.php/dd/article/view/609
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات