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Iranian Journal of Medical Physics، جلد ۷، شماره ۲، صفحات ۵۷-۶۳
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چکیده فارسی مقاله
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عنوان انگلیسی Gamma Knife Simulation Using the MCNP4C Code and the Zubal Phantom and Comparison with Experimental Data
چکیده انگلیسی مقاله Introduction: Gamma Knife is an instrument specially designed for treating brain disorders. In Gamma Knife, there are 201 narrow beams of cobalt-60 sources that intersect at an isocenter point to treat brain tumors. The tumor is placed at the isocenter and is treated by the emitted gamma rays. Therefore, there is a high dose at this point and a low dose is delivered to the normal tissue surrounding the tumor. Material and Method: In the current work, the MCNP simulation code was used to simulate the Gamma Knife. The calculated values were compared to the experimental ones and previous works. Dose distribution was compared for different collimators in a water phantom and the Zubal brain-equivalent phantom. The dose profiles were obtained along the x, y and z axes. Result: The evaluation of the developed code was performed using experimental data and we found a good agreement between our simulation and experimental data. Discussion: Our results showed that the skull bone has a high contribution to both scatter and absorbed dose. In other words, inserting the exact material of brain and other organs of the head in digital phantom improves the quality of treatment planning. This work is regarding the measurement of absorbed dose and improving the treatment planning procedure in Gamma-Knife radiosurgery in the brain.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله سمیه غلامی | somayeh gholami
m.sc., nuclear engineering dept., shahid beheshti university, tehran, iran

سازمان اصلی تایید شده: دانشگاه شهید بهشتی (Shahid beheshti university)

علیرضا کمالی اصل | alireza kamali asl
assistant professor, nuclear engineering dept., shahid beheshti university, tehran, iran

سازمان اصلی تایید شده: دانشگاه شهید بهشتی (Shahid beheshti university)

سید محمود آقامیری | seyed mahmood aghamiri
assistant professor, nuclear engineering dept., shahid beheshti university, tehran, iran

سازمان اصلی تایید شده: دانشگاه شهید بهشتی (Shahid beheshti university)

محمود اله وردی | mahmood allahverdi
assistant professor, medical physics dept., tehran university, tehran, iran

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

نشانی اینترنتی http://ijmp.mums.ac.ir/article_7262.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Paper
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