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Iranian Journal of Medical Physics، جلد ۵، شماره Issue ۱,۲، صفحات ۱-۸
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عنوان انگلیسی Study of Gentamicin Effect on Staphylococcus Aureus in the Presence of Electromagnetic Field
چکیده انگلیسی مقاله Introduction: Nowadays the medical, therapeutic and pharmacological application of magnetic fields (MF) and its biological effect has raised question about the safety of MF. This study aimed at scrutinizing the effect of static MF on the resistance of S. aureus to antibiotic. Materials and Methods: This prospective, case–control study was conducted to evaluate the effect of low intensity (0.5 mT) static MF on the growth rate and the antibiotic resistance of S. aureus sensitive to gentamicin. The studied bacterium is a nosocomial type and the growth rate was calculated by colony counting to understand the effect of MF on it. In the next stage, the rate of bacterial growth along with the different concentration of antibiotic was studied and the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were determined. Results: It is concluded that the 0.5 mT MF didn't affect the growth rate of S. aureus after 24 and 48 hours. The 0.5 mT MF induced a 50 percent decline of MIC and MBC of gentamicin after a 48 hour incubation (MIC = 4 6g /cc, MBC = 8 6g /cc in the case group vs. MIC = 8 6g /cc, MBC = 16 6g /cc in the control group). Conclusion: Low–intensity MF didn't affect the bacterial growth rate. However, the bactericidal effects of gentamicin were greater in the presence of MF. It is possible to apply the static MF for enhancing the effect of antibiotic on S. aureus.
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نویسندگان مقاله اصغر تنومند | asghar tanomand
instructor, maragheh faculty of nursing- tabriz university of medical sciences, tabriz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

امیر افشین خاکی | amir afshin khaki
associate professor, department of anatomical sciences, tabriz university of medical sciences and national public health of management center, tabriz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

حسین مهراد | hossin mehrad
instructor, department of medical, islamic azad university, tabriz, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

حسن منتظم | hassan montazam
instructor, department of microbiology, islamic azad university, bonab, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

مقصود کفشنوچی | maghasood kafshnochi
instructor, department of microbiology, islamic azad university, bonab, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

نشانی اینترنتی http://ijmp.mums.ac.ir/article_7521.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Paper
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