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Iranian Journal of Blood and Cancer، جلد ۱۰، شماره ۲، صفحات ۳۵-۳۸
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عنوان انگلیسی In vitro Evaluation of the antibacterial activity of Platelet-rich Plasma against Selected Oral and Periodontal Pathogens
چکیده انگلیسی مقاله Background: Despite the availability of a wide range of antibiotics, bacterial infections are among important challenges for the healthcare system. Therefore, the introduction of new antimicrobial preparations such as platelet-rich plasma (PRP) could be suggested theoretically as a preventive measure for bacterial infections. We aimed to evaluate the in vitro antibacterial activity of PRP against three common oral bacteria. Methods: In vitro antibacterial activity of PRP against Streptococcus Mitis, Streptococcus Mutans, and Neisseria Lactamica as three common oral/dental bacteria was determined by disc diffusion method. Baseline antibacterial activity was assessed by measuring the diameter zone of inhibition after 24 hours of incubation at 37 °C. Results: PRP had strong in vitro antibacterial activity against Streptococcus Mitis, Streptococcus Mutans and Neisseria Lactamica with the mean zone of inhibition diameters of 6.73±0.52, 5.8±0.43 and 6.67±0.43 mm, respectively. Conclusion: PRP is an effective antibacterial agent along with conventional antibiotic treatments against oral and periodontal infections.
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نویسندگان مقاله | Shafagh Rostami
Department of Pharmaceutics, Faculty of Pharmacy, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran/ Iran


| Mojgan Pourmokhtar
Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran/Iran
نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-204-3&slc_lang=en&sid=1
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Infectious Diseases
نوع مقاله منتشر شده پژوهشی
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