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Basic and Clinical Cancer Research، جلد ۶، شماره ۱، صفحات ۳۳-۳۷
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عنوان انگلیسی Choriocarcinoma Metastatic to the Kidney in Amenorrheic Woman Following Normal Vaginal Delivery
چکیده انگلیسی مقاله Gestational choriocarcinoma usually occurs following an intrauterine pregnancy. We report a case of metastatic choriocarcinoma to the left kidney and lungs with long term intermittent amenorrhea and vaginal bleeding after a normal vaginal delivery. A 43 year old rural woman presented with three years intermittent amenorrhea and vaginal bleeding following normal vaginal delivery. She also complained of gross hematuria and left flank pain and had a rising titer of serum β- hCG. Pathologic examination of endometrial curettage specimen revealed choriocarcinoma. Ultrasound revealed enlarged uterus involved by an irregular mass with heterogenous echo pattern and extensive myometrial invasion. A mass with similar echo pattern was also evident in the left kidney.Computerized tomography confirmed the intrauterine mass and involvement of the left kidney. On chest X ray, metastatic nodules were seen in both lungs and in the left retrocardiac space. The patient underwent chemotherapy with EMA-CO regimen (etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine/oncovine). During chemotherapy, she became pancytopenic and febrile. This condition was successfully managed with G-CSF, leukovorin and antibiotics. The patient is now well and still under the chemotherapy. Her serum β- hCG level has fell to 6 IU/ml.
کلیدواژه‌های انگلیسی مقاله choriocarcinoma,amenorrhea,renal metastasis
نویسندگان مقاله فریبا بهنام فر | fariba behnamfar
associate professor, department of obstetrics and gynecology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

فرشته محمدی زاده | fereshteh mohammadizadeh
associate professor, department of pathology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

لیلا هاشمی | leila hashemi
resident of obstetrics and gynecology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

سمیه sheikhalian | somayeh sheikhalian
resident of obstetrics and gynecology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://bccr.tums.ac.ir/index.php/bccrj/article/view/58
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Case Reports
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