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Iranian Journal of Public Health، جلد ۴۷، شماره ۹، صفحات ۱۳۲۶-۱۳۳۴
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عنوان انگلیسی Dietary and the Risk of Sporadic Colorectal Cancer in China: A Case-control Study
چکیده انگلیسی مقاله Abstract Background: High-fat diets have been considered a risk factor for sporadic colorectal cancer (CRC) in Western countries. However, data for this phenomenon are lacking in China. The purpose of this study was to comprehensively evaluate the association between diet and the risk for sporadic CRC in Shandong Province, China. Methods: In this case-control study, 317 patients with sporadic CRC and 317 controls were collected in Shandong Province, China. All the samples were collected on the basis of rigorous screening criteria. The data were analyzed using a χ 2 test, univariate or multivariate conditional logistic regression, and stratified analysis. Results: Multivariate logistic regression showed that the following are risk factors for sporadic CRC (all P < 0.05): consumption of pork, fried food or barbecued meat; high Body Mass Index (BMI); alcohol abuse; psychosis; and the presence of a factory causing pollution near the home. Moreover, univariate analysis revealed the following qualities were also positively associated with CRC (all P < 0.05): intake of animal oil, consuming brawn and kipper, smoking, exhibiting frequent anger, and poor sleep quality. Eating fresh fruit was inversely correlated with the incidence of CRC ( P =0.012). Further stratified analysis demonstrated that BMI and the consumption of fried food, barbecued meat, or garlic were correlated with colon cancer. However, alcohol abuse and psychosis were related to an increased risk for rectal cancer. Conclusion: Dietary factors are related to sporadic CRC in Shandong Province. Future interventions should focus on reducing the related risk factors while advocating for practice of the protective factors.
کلیدواژه‌های انگلیسی مقاله Colorectal neoplasms, Diet, Risk factors
نویسندگان مقاله | Wenfei WANG
Qilu Hospital, Shandong University, 107 Wenhua Xi Road, Jinan 250012, China


| Zhaogang DONG
Qilu Hospital, Shandong University, 107 Wenhua Xi Road, Jinan 250012, China


| Xin ZHANG
Qilu Hospital, Shandong University, 107 Wenhua Xi Road, Jinan 250012, China


| Wei LI
Qilu Hospital, Shandong University, 107 Wenhua Xi Road, Jinan 250012, China


| Peilong LI
Humanistic Medicine Research Center, Shandong University, 107 Wenhua Xi Road, Jinan 250012, China Qilu Hospital, Shandong University, 107 Wenhua Xi Road, Jinan 250012, China


| Xiaoyang CHEN


نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/14587
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