این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Dental Research Journal، جلد ۹، شماره ۴، صفحات ۰-۰
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عنوان انگلیسی Evaluation of the therapeutic effects of Aloe vera gel on minor recurrent aphthous stomatitis
چکیده انگلیسی مقاله Background: Aphthous ulcer is one of the most common diseases of the oral cavity with no known effective treatment so far, which could cause severe discomfort in patients. Aloe vera (A.V.) is a tropical plant with anti-inflammatory and immunostimulant effects, which could be of benefit in a diversity of wound healing conditions. The aim of this study is to evaluate topically administered A.V. gel on oral cavity minor aphthous healing. Materials and Methods: As a double-blind (case control) clinical trial, 40 patients with oral minor aphthous lesions were randomly allocated in either the case group (A.V. gel) or the control (placebo) group. The healing time (days after gel application), patient’s pain score; the lesion and its surrounding inflammation diameters were recorded for 2 weeks. The obtained results were analyzed by either “Fishers exact” or t -student test using SPSS software. Results: The mean (±SD) of patients’ age was 29.25 ± 8.48 and 27.95 ± 7.96 years in the control and A.V.-treated groups, respectively, which were not significantly different ( P > 0.05). The duration of complete wound healing, pain score, wound size and inflammation zone diameter in the A.V.- treated group were significantly lower than the control group ( P ≤ 0.05) on specific time points after treatment. Conclusion: It seems likely that A.V. 2% oral gel is not only effective in decreasing the recurrent aphthous stomatitis patients’ pain score and wound size but also decreases the aphthous wound healing period. Key Words: Aloe vera, aphthous stomatitis, immunomodulation, mouth diseases
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نویسندگان مقاله ندا بابایی | neda babaee


ابراهیم ذبیحی | ebrahim zabihi


سامان محسنی | saman mohseni


علی اکبر مقدم نیا | ali akbar moghadamnia


نشانی اینترنتی http://drj.mui.ac.ir/index.php/drj/article/view/1151
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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