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Dental Research Journal، جلد ۸، شماره ۵، صفحات ۰-۰
عنوان فارسی
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عنوان انگلیسی Clinical evaluation of the essential oil of Pelargonium graveolens for the treatment of denture stomatitis
چکیده انگلیسی مقاله Background: Natural products are proved to play a good role as an alternative to synthetic chemicals in clinical conditions. Previous studies showed that Pelargonium graveolens has anti-inflammatory and antifungal activity against Candida albicans . The aim of this study was to evaluate the efficacy of essential oil of Pelargonium graveolens in the treatment of denture stomatitis . Materials and Methods: In this double-blind randomized clinical trial conducted in Isfahan (Iran), 80 (51 females and 29 males) eligible wearers of complete denture were included . According to the patients’ profiles number, they randomly divided to 2 groups of 40 patients’ case and 40 patients control treated with Pelargonium 1% gel or placebo, respectively. They were recommended to apply the gel twice daily for a 14-day course. All data were analyzed using SPSS® for windows (v.18). We have used the c2 test for analyzing qualitative and Student t -test for quantitative data considering as P < 0.05 as significant. Results: According to mycological data and clinical observation after treatment in the case group, 34% of patients had been improved completely, 56% partially and 10% had no improvement. In the control group, 5% of patients had complete recovery, 25% partial recovery, and 70% no improvement. A significant reduction in fungal growth was observed in case group rather than the control group ( P value< 0.0001). Conclusion: It seems that the application of a 1% Geranium oil topical gel formulation is more effective than placebo in the treatment of denture stomatitis. Key Words: Candida albicans , denture stomatitis, Pelargonium graveolens
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله علی محمد سبزقبایی | ali mohammad sabzghabaee


زهرا شیر دره | zahra shirdare


بهناز عبادیان | behnaz ebadian


ابوالفضل اصلانی | abolfazl aslani


علیرضا قنادی | alireza ghannadi


نشانی اینترنتی http://drj.mui.ac.ir/index.php/drj/article/view/951
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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