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Caspian Journal of Internal Medicine، جلد ۶، شماره ۳، صفحات ۱۷۴-۱۷۶
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عنوان انگلیسی Isolated thrombocytopenia report of a rare presentation of childhood Systemic Lupus Erythematosus
چکیده انگلیسی مقاله  Background: Systemic lupus erythematosus (SLE) has various presentations in children. Hematologic abnormalities is common in childhood onset of SLE, however, isolated thrombocytopenia is relatively rare. Thus, we present a child with isolated thrombocytopenia as a rare presentation of SLE. Case presentation: A 12-year-old boy with chief complaints of loss of appetite, weight loss, decreased platelet count (8000/µL) and lymph node enlargement was referred to our hospital. Biopsy of lymph node showed reactive lymphadenopathy. Investigations regarding infectious disease was negative. Platelet count remained low after low dose steroidned therapy. Antinuclear antibody (ANA) and anti-double stranded DNA antibody screening tests were positive with titer of 1/62 and 1/54, respectively. Therefore, juvenile SLE was considered as the final diagnosis and raising the dose of prednisolone to 2mg/kg/day was associated with increasing platelet count to 40000/µL and a week later to 96000/µL. Conclusion: The findings of this study indicate that in cases with isolated thrombocytopenia refractory to conventional dose of steroids, SLE should be considered. This study justifies serum ANA and anti DNA assessment in children with thrombocytopenia 
کلیدواژه‌های انگلیسی مقاله Systemic Lupus Erythematosus, Thrombocytopenia, Pediatrics
نویسندگان مقاله احمد تمدنی | ahmad tamaddoni
non-communicable pediatric diseases research center, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

بهناز یوسف قهاری | behnaz yousefghahari
department of internal medicine, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

افشین خانی | afshin khani
student research committee, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

محمدرضا اسماعیلی دوکی | mohammadreza esmaeilidooki
non-communicable pediatric diseases research center, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

رحیم سوادکوهی براری | rahim barari sawadkouhi
non-communicable pediatric diseases research center, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

ایرج محمدزاده | iraj mohammadzadeh
non-communicable pediatric diseases research center, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

نشانی اینترنتی http://www.caspjim.com/browse.php?a_code=A-10-35-1&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Infectious Diseases
نوع مقاله منتشر شده case report
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